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GRIK2 is a target for bladder cancer stem-like cell-targeting immunotherapy.
Miyata H, Hirohashi Y, Yamada S, Yanagawa J, Murai A, Hashimoto S, Tokita S, Hori K, Abe T, Kubo T, Tsukahara T, Kanaseki T, Shinohara N, Torigoe T. Miyata H, et al. Among authors: murai a. Cancer Immunol Immunother. 2022 Apr;71(4):795-806. doi: 10.1007/s00262-021-03025-z. Epub 2021 Aug 18. Cancer Immunol Immunother. 2022. PMID: 34405274 Free PMC article.
Establishment and Analysis of Cancer Stem-Like and Non-Cancer Stem-Like Clone Cells from the Human Colon Cancer Cell Line SW480.
Takaya A, Hirohashi Y, Murai A, Morita R, Saijo H, Yamamoto E, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Tamura Y, Takemasa I, Kondo T, Sato N, Torigoe T. Takaya A, et al. Among authors: murai a. PLoS One. 2016 Jul 14;11(7):e0158903. doi: 10.1371/journal.pone.0158903. eCollection 2016. PLoS One. 2016. PMID: 27415781 Free PMC article.
Identification and functional analysis of variants of a cancer/testis antigen LEMD1 in colorectal cancer stem-like cells.
Takeda R, Hirohashi Y, Shen M, Wang L, Ogawa T, Murai A, Yamamoto E, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Nishidate T, Okita K, Kutomi G, Sato N, Takemasa I, Torigoe T. Takeda R, et al. Among authors: murai a. Biochem Biophys Res Commun. 2017 Apr 8;485(3):651-657. doi: 10.1016/j.bbrc.2017.02.081. Epub 2017 Feb 20. Biochem Biophys Res Commun. 2017. PMID: 28219643
GRIK2 has a role in the maintenance of urothelial carcinoma stem-like cells, and its expression is associated with poorer prognosis.
Inoue R, Hirohashi Y, Kitamura H, Nishida S, Murai A, Takaya A, Yamamoto E, Matsuki M, Tanaka T, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Sato N, Masumori N, Torigoe T. Inoue R, et al. Among authors: murai a. Oncotarget. 2017 Apr 25;8(17):28826-28839. doi: 10.18632/oncotarget.16259. Oncotarget. 2017. PMID: 28418868 Free PMC article.
Cellular stress induces cancer stem-like cells through expression of DNAJB8 by activation of heat shock factor 1.
Kusumoto H, Hirohashi Y, Nishizawa S, Yamashita M, Yasuda K, Murai A, Takaya A, Mori T, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Kondo T, Sato N, Hara I, Torigoe T. Kusumoto H, et al. Among authors: murai a. Cancer Sci. 2018 Mar;109(3):741-750. doi: 10.1111/cas.13501. Epub 2018 Feb 20. Cancer Sci. 2018. PMID: 29316077 Free PMC article.
Case report: Long-term survival of a pancreatic cancer patient immunized with an SVN-2B peptide vaccine.
Shima H, Kutomi G, Satomi F, Imamura M, Kimura Y, Mizuguchi T, Watanabe K, Takahashi A, Murai A, Tsukahara T, Kanaseki T, Hirohashi Y, Iwayama Y, Tsuruma T, Kameshima H, Sato N, Torigoe T, Takemasa I. Shima H, et al. Among authors: murai a. Cancer Immunol Immunother. 2018 Oct;67(10):1603-1609. doi: 10.1007/s00262-018-2217-x. Epub 2018 Aug 1. Cancer Immunol Immunother. 2018. PMID: 30069687 Free PMC article.
Clonal analysis revealed functional heterogeneity in cancer stem-like cell phenotypes in uterine endometrioid adenocarcinoma.
Tabuchi Y, Hirohashi Y, Hashimoto S, Mariya T, Asano T, Ikeo K, Kuroda T, Mizuuchi M, Murai A, Uno S, Kawai N, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Saito T, Torigoe T. Tabuchi Y, et al. Among authors: murai a. Exp Mol Pathol. 2019 Feb;106:78-88. doi: 10.1016/j.yexmp.2018.11.013. Epub 2018 Nov 30. Exp Mol Pathol. 2019. PMID: 30503404
ABCG2 expression is related to low 5-ALA photodynamic diagnosis (PDD) efficacy and cancer stem cell phenotype, and suppression of ABCG2 improves the efficacy of PDD.
Kawai N, Hirohashi Y, Ebihara Y, Saito T, Murai A, Saito T, Shirosaki T, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Shichinohe T, Li L, Hirano S, Torigoe T. Kawai N, et al. Among authors: murai a. PLoS One. 2019 May 13;14(5):e0216503. doi: 10.1371/journal.pone.0216503. eCollection 2019. PLoS One. 2019. PMID: 31083682 Free PMC article.
Neuregulin-1-β1 and γ-secretase play a critical role in sphere-formation and cell survival of urothelial carcinoma cancer stem-like cells.
Matsuki M, Inoue R, Murai A, Kubo T, Hashimoto S, Murata K, Kanaseki T, Tsukahara T, Nishida S, Tanaka T, Kitamura H, Masumori N, Hirohashi Y, Torigoe T. Matsuki M, et al. Among authors: murai a. Biochem Biophys Res Commun. 2021 May 7;552:128-135. doi: 10.1016/j.bbrc.2021.03.038. Epub 2021 Mar 19. Biochem Biophys Res Commun. 2021. PMID: 33744760
Tumor-infiltrating CD8+ T cells recognize a heterogeneously expressed functional neoantigen in clear cell renal cell carcinoma.
Matsuki M, Hirohashi Y, Nakatsugawa M, Murai A, Kubo T, Hashimoto S, Tokita S, Murata K, Kanaseki T, Tsukahara T, Nishida S, Tanaka T, Kitamura H, Masumori N, Torigoe T. Matsuki M, et al. Among authors: murai a. Cancer Immunol Immunother. 2022 Apr;71(4):905-918. doi: 10.1007/s00262-021-03048-6. Epub 2021 Sep 7. Cancer Immunol Immunother. 2022. PMID: 34491407 Free PMC article.
288 results