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The dimeric form of CXCL12 binds to atypical chemokine receptor 1.
Gutjahr JC, Crawford KS, Jensen DR, Naik P, Peterson FC, Samson GPB, Legler DF, Duchene J, Veldkamp CT, Rot A, Volkman BF. Gutjahr JC, et al. Among authors: legler df. Sci Signal. 2021 Aug 17;14(696):eabc9012. doi: 10.1126/scisignal.abc9012. Sci Signal. 2021. PMID: 34404752 Free PMC article.
Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4.
Collins PJ, McCully ML, Martínez-Muñoz L, Santiago C, Wheeldon J, Caucheteux S, Thelen S, Cecchinato V, Laufer JM, Purvanov V, Monneau YR, Lortat-Jacob H, Legler DF, Uguccioni M, Thelen M, Piguet V, Mellado M, Moser B. Collins PJ, et al. Among authors: legler df. FASEB J. 2017 Jul;31(7):3084-3097. doi: 10.1096/fj.201700013R. Epub 2017 Mar 30. FASEB J. 2017. PMID: 28360196 Free PMC article.
Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7.
Jørgensen AS, Larsen O, Uetz-von Allmen E, Lückmann M, Legler DF, Frimurer TM, Veldkamp CT, Hjortø GM, Rosenkilde MM. Jørgensen AS, et al. Among authors: legler df. Front Immunol. 2019 Sep 13;10:2156. doi: 10.3389/fimmu.2019.02156. eCollection 2019. Front Immunol. 2019. PMID: 31572374 Free PMC article.
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