Barnes R - Search Results

1

Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNA.

Pan H, Kaur P, Barnes R, Detwiler AC, Sanford SL, Liu M, Xu P, Mahn C, Tang Q, Hao P, Bhattaram D, You C, Gu X, Lu W, Piehler J, Xu G, Weninger K, Riehn R, Opresko PL, Wang H. Pan H, et al. Among authors: barnes r. J Biol Chem. 2021 Sep;297(3):101080. doi: 10.1016/j.jbc.2021.101080. Epub 2021 Aug 14. J Biol Chem. 2021. PMID: 34403696 Free PMC article.

2

The impact of oxidative DNA damage and stress on telomere homeostasis.

Barnes RP, Fouquerel E, Opresko PL. Barnes RP, et al. Mech Ageing Dev. 2019 Jan;177:37-45. doi: 10.1016/j.mad.2018.03.013. Epub 2018 Mar 28. Mech Ageing Dev. 2019. PMID: 29604323 Free PMC article. Review.

3

Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis.

Fouquerel E, Barnes RP, Uttam S, Watkins SC, Bruchez MP, Opresko PL. Fouquerel E, et al. Mol Cell. 2019 Jul 11;75(1):117-130.e6. doi: 10.1016/j.molcel.2019.04.024. Epub 2019 May 14. Mol Cell. 2019. PMID: 31101499 Free PMC article.

4

Measuring UV Photoproduct Repair in Isolated Telomeres and Bulk Genomic DNA.

Fouquerel E, Barnes RP, Wang H, Opresko PL. Fouquerel E, et al. Methods Mol Biol. 2019;1999:295-306. doi: 10.1007/978-1-4939-9500-4_20. Methods Mol Biol. 2019. PMID: 31127586 Free PMC article.

5

TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA.

Kaur P, Barnes R, Pan H, Detwiler AC, Liu M, Mahn C, Hall J, Messenger Z, You C, Piehler J, Smart RC, Riehn R, Opresko PL, Wang H. Kaur P, et al. Among authors: barnes r. Nucleic Acids Res. 2021 Dec 16;49(22):13000-13018. doi: 10.1093/nar/gkab1142. Nucleic Acids Res. 2021. PMID: 34883513 Free PMC article.

6

Global and transcription-coupled repair of 8-oxoG is initiated by nucleotide excision repair proteins.

Kumar N, Theil AF, Roginskaya V, Ali Y, Calderon M, Watkins SC, Barnes RP, Opresko PL, Pines A, Lans H, Vermeulen W, Van Houten B. Kumar N, et al. Nat Commun. 2022 Feb 21;13(1):974. doi: 10.1038/s41467-022-28642-9. Nat Commun. 2022. PMID: 35190564 Free PMC article.

7

Targeted Formation of 8-Oxoguanine in Telomeres.

Barnes RP, Thosar SA, Fouquerel E, Opresko PL. Barnes RP, et al. Methods Mol Biol. 2022;2444:141-159. doi: 10.1007/978-1-0716-2063-2_9. Methods Mol Biol. 2022. PMID: 35290636

8

Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening.

Barnes RP, de Rosa M, Thosar SA, Detwiler AC, Roginskaya V, Van Houten B, Bruchez MP, Stewart-Ornstein J, Opresko PL. Barnes RP, et al. Nat Struct Mol Biol. 2022 Jul;29(7):639-652. doi: 10.1038/s41594-022-00790-y. Epub 2022 Jun 30. Nat Struct Mol Biol. 2022. PMID: 35773409 Free PMC article.

9

Premature aging is associated with higher levels of 8-oxoguanine and increased DNA damage in the Polg mutator mouse.

Yu T, Slone J, Liu W, Barnes R, Opresko PL, Wark L, Mai S, Horvath S, Huang T. Yu T, et al. Among authors: barnes r. Aging Cell. 2022 Sep;21(9):e13669. doi: 10.1111/acel.13669. Epub 2022 Aug 22. Aging Cell. 2022. PMID: 35993394 Free PMC article.

10

Telomere Fragility and MiDAS: Managing the Gaps at the End of the Road.

Barnes RP, Thosar SA, Opresko PL. Barnes RP, et al. Genes (Basel). 2023 Jan 29;14(2):348. doi: 10.3390/genes14020348. Genes (Basel). 2023. PMID: 36833275 Free PMC article. Review.

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