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Circulating syndecan-1 is reduced in pregnancies with poor fetal growth and its secretion regulated by matrix metalloproteinases and the mitochondria.
Garcha D, Walker SP, MacDonald TM, Hyett J, Jellins J, Myers J, Illanes SE, Nien JK, Schepeler M, Keenan E, Whigham CA, Cannon P, Murray E, Nguyen TV, Kandel M, Masci J, Murphy C, Cruickshank T, Pritchard N, Hannan NJ, Brownfoot F, Roddy Mitchell A, Middleton A, Pell G, Wong GP, Tong S, Kaitu'u-Lino TJ. Garcha D, et al. Among authors: middleton a. Sci Rep. 2021 Aug 16;11(1):16595. doi: 10.1038/s41598-021-96077-1. Sci Rep. 2021. PMID: 34400721 Free PMC article.
Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction.
Kaitu'u-Lino TJ, MacDonald TM, Cannon P, Nguyen TV, Hiscock RJ, Haan N, Myers JE, Hastie R, Dane KM, Middleton AL, Bittar I, Sferruzzi-Perri AN, Pritchard N, Harper A, Hannan NJ, Kyritsis V, Crinis N, Hui L, Walker SP, Tong S. Kaitu'u-Lino TJ, et al. Among authors: middleton al. Nat Commun. 2020 May 15;11(1):2411. doi: 10.1038/s41467-020-16346-x. Nat Commun. 2020. PMID: 32415092 Free PMC article.
Circulating Tissue Factor Pathway Inhibitor (TFPI) is increased preceding preeclampsia diagnosis and in established preeclampsia.
MacDonald TM, Tong S, Myers J, Cannon P, Nguyen TV, Keenan E, Murray E, Harper A, Pritchard N, Hannan NJ, Dane KM, Middleton AL, Kyritsis VP, Walker SP, Kaitu'u-Lino TJ. MacDonald TM, et al. Among authors: middleton al. Placenta. 2021 Feb;105:32-40. doi: 10.1016/j.placenta.2021.01.018. Epub 2021 Jan 22. Placenta. 2021. PMID: 33529886
Circulating Growth Differentiation Factor 15 Is Increased Preceding Preeclampsia Diagnosis: Implications as a Disease Biomarker.
Cruickshank T, MacDonald TM, Walker SP, Keenan E, Dane K, Middleton A, Kyritsis V, Myers J, Cluver C, Hastie R, Bergman L, Garcha D, Cannon P, Murray E, Nguyen TV, Hiscock R, Pritchard N, Hannan NJ, Tong S, Kaitu'u-Lino TJ. Cruickshank T, et al. Among authors: middleton a. J Am Heart Assoc. 2021 Aug 17;10(16):e020302. doi: 10.1161/JAHA.120.020302. Epub 2021 Aug 13. J Am Heart Assoc. 2021. PMID: 34387117 Free PMC article.
Assessing the sensitivity of placental growth factor and soluble fms-like tyrosine kinase 1 at 36 weeks' gestation to predict small-for-gestational-age infants or late-onset preeclampsia: a prospective nested case-control study.
MacDonald TM, Tran C, Kaitu'u-Lino TJ, Brennecke SP, Hiscock RJ, Hui L, Dane KM, Middleton AL, Cannon P, Walker SP, Tong S. MacDonald TM, et al. BMC Pregnancy Childbirth. 2018 Aug 31;18(1):354. doi: 10.1186/s12884-018-1992-x. BMC Pregnancy Childbirth. 2018. PMID: 30170567 Free PMC article.
Screening circulating proteins to identify biomarkers of fetal macrosomia.
Cruickshank T, Kaitu'u-Lino TJ, Cannon P, Harper A, Nguyen TV, Dane KM, Middleton AL, Kyritsis VP, Hastie R, Tong S, Walker SP, MacDonald TM. Cruickshank T, et al. Among authors: middleton al. BMC Res Notes. 2019 Sep 18;12(1):587. doi: 10.1186/s13104-019-4625-1. BMC Res Notes. 2019. PMID: 31533811 Free PMC article.
565 results