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Targeted inhibition of eIF4A suppresses B-cell receptor-induced translation and expression of MYC and MCL1 in chronic lymphocytic leukemia cells.
Wilmore S, Rogers-Broadway KR, Taylor J, Lemm E, Fell R, Stevenson FK, Forconi F, Steele AJ, Coldwell M, Packham G, Yeomans A. Wilmore S, et al. Among authors: rogers broadway kr. Cell Mol Life Sci. 2021 Sep;78(17-18):6337-6349. doi: 10.1007/s00018-021-03910-x. Epub 2021 Aug 16. Cell Mol Life Sci. 2021. PMID: 34398253 Free PMC article.
BCR signaling contributes to autophagy regulation in chronic lymphocytic leukemia.
Smith LD, Minton AR, Blunt MD, Karydis LI, Dutton DA, Rogers-Broadway KR, Dobson R, Liu R, Norster F, Hogg E, Ashton-Key M, Strefford JC, Jia L, Efremov DG, Helgason GV, Johnson PWM, Stevenson FK, Forconi F, Cragg MS, Tumbarello DA, Packham G, Steele AJ. Smith LD, et al. Among authors: rogers broadway kr. Leukemia. 2020 Feb;34(2):640-644. doi: 10.1038/s41375-019-0557-y. Epub 2019 Aug 28. Leukemia. 2020. PMID: 31462734 Free PMC article. No abstract available.
B-cell receptor signaling induces proteasomal degradation of PDCD4 via MEK1/2 and mTORC1 in malignant B cells.
Taylor J, Wilmore S, Marriot S, Rogers-Broadway KR, Fell R, Minton AR, Branch T, Ashton-Key M, Coldwell M, Stevenson FK, Forconi F, Steele AJ, Packham G, Yeomans A. Taylor J, et al. Among authors: rogers broadway kr. Cell Signal. 2022 Jun;94:110311. doi: 10.1016/j.cellsig.2022.110311. Epub 2022 Mar 16. Cell Signal. 2022. PMID: 35306137 Free PMC article.
Network analysis reveals a major role for 14q32 cluster miRNAs in determining transcriptional differences between IGHV-mutated and unmutated CLL.
Bryant D, Smith L, Rogers-Broadway KR, Karydis L, Woo J, Blunt MD, Forconi F, Stevenson FK, Goodnow C, Russell A, Humburg P, Packham G, Steele AJ, Strefford JC. Bryant D, et al. Among authors: rogers broadway kr. Leukemia. 2023 Jul;37(7):1454-1463. doi: 10.1038/s41375-023-01918-9. Epub 2023 May 11. Leukemia. 2023. PMID: 37169950 Free PMC article.
Differential expression of mTOR components in endometriosis and ovarian cancer: Effects of rapalogues and dual kinase inhibitors on mTORC1 and mTORC2 stoichiometry.
Rogers-Broadway KR, Kumar J, Sisu C, Wander G, Mazey E, Jeyaneethi J, Pados G, Tsolakidis D, Klonos E, Grunt T, Hall M, Chatterjee J, Karteris E. Rogers-Broadway KR, et al. Int J Mol Med. 2019 Jan;43(1):47-56. doi: 10.3892/ijmm.2018.3967. Epub 2018 Oct 31. Int J Mol Med. 2019. PMID: 30387804 Free PMC article.
Elucidating the role of DEPTOR in Alzheimer's disease.
Davies J, Zachariades E, Rogers-Broadway KR, Karteris E. Davies J, et al. Among authors: rogers broadway kr. Int J Mol Med. 2014 Nov;34(5):1195-200. doi: 10.3892/ijmm.2014.1895. Epub 2014 Aug 12. Int J Mol Med. 2014. PMID: 25119265 Free PMC article.