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Targeted inhibition of eIF4A suppresses B-cell receptor-induced translation and expression of MYC and MCL1 in chronic lymphocytic leukemia cells.
Wilmore S, Rogers-Broadway KR, Taylor J, Lemm E, Fell R, Stevenson FK, Forconi F, Steele AJ, Coldwell M, Packham G, Yeomans A. Wilmore S, et al. Among authors: coldwell m. Cell Mol Life Sci. 2021 Sep;78(17-18):6337-6349. doi: 10.1007/s00018-021-03910-x. Epub 2021 Aug 16. Cell Mol Life Sci. 2021. PMID: 34398253 Free PMC article.
B-cell receptor signaling induces proteasomal degradation of PDCD4 via MEK1/2 and mTORC1 in malignant B cells.
Taylor J, Wilmore S, Marriot S, Rogers-Broadway KR, Fell R, Minton AR, Branch T, Ashton-Key M, Coldwell M, Stevenson FK, Forconi F, Steele AJ, Packham G, Yeomans A. Taylor J, et al. Among authors: coldwell m. Cell Signal. 2022 Jun;94:110311. doi: 10.1016/j.cellsig.2022.110311. Epub 2022 Mar 16. Cell Signal. 2022. PMID: 35306137 Free PMC article.
WDHD1 is essential for the survival of PTEN-inactive triple-negative breast cancer.
Ertay A, Liu H, Liu D, Peng P, Hill C, Xiong H, Hancock D, Yuan X, Przewloka MR, Coldwell M, Howell M, Skipp P, Ewing RM, Downward J, Wang Y. Ertay A, et al. Among authors: coldwell m. Cell Death Dis. 2020 Nov 21;11(11):1001. doi: 10.1038/s41419-020-03210-5. Cell Death Dis. 2020. PMID: 33221821 Free PMC article.
Paracrine signalling during ZEB1-mediated epithelial-mesenchymal transition augments local myofibroblast differentiation in lung fibrosis.
Yao L, Conforti F, Hill C, Bell J, Drawater L, Li J, Liu D, Xiong H, Alzetani A, Chee SJ, Marshall BG, Fletcher SV, Hancock D, Coldwell M, Yuan X, Ottensmeier CH, Downward J, Collins JE, Ewing RM, Richeldi L, Skipp P, Jones MG, Davies DE, Wang Y. Yao L, et al. Among authors: coldwell m. Cell Death Differ. 2019 May;26(5):943-957. doi: 10.1038/s41418-018-0175-7. Epub 2018 Jul 26. Cell Death Differ. 2019. PMID: 30050057 Free PMC article.
Pharmacological characterisation of human 5-HT2 receptor subtypes.
Jerman JC, Brough SJ, Gager T, Wood M, Coldwell MC, Smart D, Middlemiss DN. Jerman JC, et al. Among authors: coldwell mc. Eur J Pharmacol. 2001 Feb 23;414(1):23-30. doi: 10.1016/s0014-2999(01)00775-0. Eur J Pharmacol. 2001. PMID: 11230991
Pharmacological actions of a novel, high-affinity, and selective human dopamine D(3) receptor antagonist, SB-277011-A.
Reavill C, Taylor SG, Wood MD, Ashmeade T, Austin NE, Avenell KY, Boyfield I, Branch CL, Cilia J, Coldwell MC, Hadley MS, Hunter AJ, Jeffrey P, Jewitt F, Johnson CN, Jones DN, Medhurst AD, Middlemiss DN, Nash DJ, Riley GJ, Routledge C, Stemp G, Thewlis KM, Trail B, Vong AK, Hagan JJ. Reavill C, et al. Among authors: coldwell mc. J Pharmacol Exp Ther. 2000 Sep;294(3):1154-65. J Pharmacol Exp Ther. 2000. PMID: 10945872
68 results