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Efficient base editing for multiple genes and loci in pigs using base editors.
Xie J, Ge W, Li N, Liu Q, Chen F, Yang X, Huang X, Ouyang Z, Zhang Q, Zhao Y, Liu Z, Gou S, Wu H, Lai C, Fan N, Jin Q, Shi H, Liang Y, Lan T, Quan L, Li X, Wang K, Lai L. Xie J, et al. Among authors: li x, li n. Nat Commun. 2019 Jun 28;10(1):2852. doi: 10.1038/s41467-019-10421-8. Nat Commun. 2019. PMID: 31253764 Free PMC article.
BMI1 enables interspecies chimerism with human pluripotent stem cells.
Huang K, Zhu Y, Ma Y, Zhao B, Fan N, Li Y, Song H, Chu S, Ouyang Z, Zhang Q, Xing Q, Lai C, Li N, Zhang T, Gu J, Kang B, Shan Y, Lai K, Huang W, Mai Y, Wang Q, Li J, Lin A, Zhang Y, Zhong X, Liao B, Lai L, Chen J, Pei D, Pan G. Huang K, et al. Among authors: li y, li j, li n. Nat Commun. 2018 Nov 7;9(1):4649. doi: 10.1038/s41467-018-07098-w. Nat Commun. 2018. PMID: 30405129 Free PMC article.
AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns.
Liang Y, Xie J, Zhang Q, Wang X, Gou S, Lin L, Chen T, Ge W, Zhuang Z, Lian M, Chen F, Li N, Ouyang Z, Lai C, Liu X, Li L, Ye Y, Wu H, Wang K, Lai L. Liang Y, et al. Among authors: li n, li l. Nucleic Acids Res. 2022 May 20;50(9):5384-5399. doi: 10.1093/nar/gkac353. Nucleic Acids Res. 2022. PMID: 35544322 Free PMC article.
Resequencing of 243 diploid cotton accessions based on an updated A genome identifies the genetic basis of key agronomic traits.
Du X, Huang G, He S, Yang Z, Sun G, Ma X, Li N, Zhang X, Sun J, Liu M, Jia Y, Pan Z, Gong W, Liu Z, Zhu H, Ma L, Liu F, Yang D, Wang F, Fan W, Gong Q, Peng Z, Wang L, Wang X, Xu S, Shang H, Lu C, Zheng H, Huang S, Lin T, Zhu Y, Li F. Du X, et al. Among authors: li f, li n. Nat Genet. 2018 Jun;50(6):796-802. doi: 10.1038/s41588-018-0116-x. Epub 2018 May 7. Nat Genet. 2018. PMID: 29736014
Cre-dependent Cas9-expressing pigs enable efficient in vivo genome editing.
Wang K, Jin Q, Ruan D, Yang Y, Liu Q, Wu H, Zhou Z, Ouyang Z, Liu Z, Zhao Y, Zhao B, Zhang Q, Peng J, Lai C, Fan N, Liang Y, Lan T, Li N, Wang X, Wang X, Fan Y, Doevendans PA, Sluijter JPG, Liu P, Li X, Lai L. Wang K, et al. Among authors: li x, li n. Genome Res. 2017 Dec;27(12):2061-2071. doi: 10.1101/gr.222521.117. Epub 2017 Nov 16. Genome Res. 2017. PMID: 29146772 Free PMC article.
Engineering CRISPR/Cpf1 with tRNA promotes genome editing capability in mammalian systems.
Wu H, Liu Q, Shi H, Xie J, Zhang Q, Ouyang Z, Li N, Yang Y, Liu Z, Zhao Y, Lai C, Ruan D, Peng J, Ge W, Chen F, Fan N, Jin Q, Liang Y, Lan T, Yang X, Wang X, Lei Z, Doevendans PA, Sluijter JPG, Wang K, Li X, Lai L. Wu H, et al. Among authors: li x, li n. Cell Mol Life Sci. 2018 Oct;75(19):3593-3607. doi: 10.1007/s00018-018-2810-3. Epub 2018 Apr 10. Cell Mol Life Sci. 2018. PMID: 29637228 Free PMC article.
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