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An end-to-end automated platform process for high-throughput engineering of next-generation multi-specific antibody therapeutics.
MAbs. 2021 Jan-Dec;13(1):1955433. doi: 10.1080/19420862.2021.1955433.
MAbs. 2021.
PMID: 34382900
Free PMC article.
Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques.
Xu L, Pegu A, Rao E, Doria-Rose N, Beninga J, McKee K, Lord DM, Wei RR, Deng G, Louder M, Schmidt SD, Mankoff Z, Wu L, Asokan M, Beil C, Lange C, Leuschner WD, Kruip J, Sendak R, Kwon YD, Zhou T, Chen X, Bailer RT, Wang K, Choe M, Tartaglia LJ, Barouch DH, O'Dell S, Todd JP, Burton DR, Roederer M, Connors M, Koup RA, Kwong PD, Yang ZY, Mascola JR, Nabel GJ.
Xu L, et al. Among authors: leuschner wd.
Science. 2017 Oct 6;358(6359):85-90. doi: 10.1126/science.aan8630. Epub 2017 Sep 20.
Science. 2017.
PMID: 28931639
Free PMC article.
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Pre-clinical development of a novel CD3-CD123 bispecific T-cell engager using cross-over dual-variable domain (CODV) format for acute myeloid leukemia (AML) treatment.
Bonnevaux H, Guerif S, Albrecht J, Jouannot E, De Gallier T, Beil C, Lange C, Leuschner WD, Schneider M, Lemoine C, Caron A, Amara C, Barrière C, Siavellis J, Bardet V, Luna E, Agrawal P, Drake DR, Rao E, Wonerow P, Carrez C, Blanc V, Hsu K, Wiederschain D, Fraenkel PG, Virone-Oddos A.
Bonnevaux H, et al. Among authors: leuschner wd.
Oncoimmunology. 2021 Aug 31;10(1):1945803. doi: 10.1080/2162402X.2021.1945803. eCollection 2021.
Oncoimmunology. 2021.
PMID: 34484869
Free PMC article.
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A multivalent antibody assembled from different building blocks using tag/catcher systems: a case study.
Schindler C, Faust C, Sjuts H, Lange C, Kühn J, Dittrich W, Leuschner WD, Schiebler W, Hofmann J, Rao E, Langer T.
Schindler C, et al. Among authors: leuschner wd.
Protein Eng Des Sel. 2022 Feb 17;35:gzac014. doi: 10.1093/protein/gzac014.
Protein Eng Des Sel. 2022.
PMID: 36373216
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Functional studies with IgM and IgA immunoglobulins: binding to pIgR, FcαμR, FcμR, and CDC activities.
Beyer H, Sommerfeld M, Grandien K, Faust C, Tillmann B, Leuschner WD, Régnier-Vigouroux A, Weil S, Rao E, Langer T.
Beyer H, et al. Among authors: leuschner wd.
APMIS. 2024 Apr;132(4):277-288. doi: 10.1111/apm.13377. Epub 2024 Jan 17.
APMIS. 2024.
PMID: 38232051
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The genome of Desulfotalea psychrophila, a sulfate-reducing bacterium from permanently cold Arctic sediments.
Rabus R, Ruepp A, Frickey T, Rattei T, Fartmann B, Stark M, Bauer M, Zibat A, Lombardot T, Becker I, Amann J, Gellner K, Teeling H, Leuschner WD, Glöckner FO, Lupas AN, Amann R, Klenk HP.
Rabus R, et al. Among authors: leuschner wd.
Environ Microbiol. 2004 Sep;6(9):887-902. doi: 10.1111/j.1462-2920.2004.00665.x.
Environ Microbiol. 2004.
PMID: 15305914
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Subtype-specific assembly of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits is mediated by their n-terminal domains.
Leuschner WD, Hoch W.
Leuschner WD, et al.
J Biol Chem. 1999 Jun 11;274(24):16907-16. doi: 10.1074/jbc.274.24.16907.
J Biol Chem. 1999.
PMID: 10358037
Free article.
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