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Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis.
Chatterjee S, Yabaji SM, Rukhlenko OS, Bhattacharya B, Waligurski E, Vallavoju N, Ray S, Kholodenko BN, Brown LE, Beeler AB, Ivanov AR, Kobzik L, Porco JA Jr, Kramnik I. Chatterjee S, et al. Among authors: kobzik l. iScience. 2021 Jul 10;24(8):102845. doi: 10.1016/j.isci.2021.102845. eCollection 2021 Aug 20. iScience. 2021. PMID: 34381970 Free PMC article.
Ipr1 gene mediates innate immunity to tuberculosis.
Pan H, Yan BS, Rojas M, Shebzukhov YV, Zhou H, Kobzik L, Higgins DE, Daly MJ, Bloom BR, Kramnik I. Pan H, et al. Among authors: kobzik l. Nature. 2005 Apr 7;434(7034):767-72. doi: 10.1038/nature03419. Nature. 2005. PMID: 15815631 Free PMC article.
The integrated stress response mediates necrosis in murine Mycobacterium tuberculosis granulomas.
Bhattacharya B, Xiao S, Chatterjee S, Urbanowski M, Ordonez A, Ihms EA, Agrahari G, Lun S, Berland R, Pichugin A, Gao Y, Connor J, Ivanov AR, Yan BS, Kobzik L, Koo BB, Jain S, Bishai W, Kramnik I. Bhattacharya B, et al. Among authors: kobzik l. J Clin Invest. 2021 Feb 1;131(3):e130319. doi: 10.1172/JCI130319. J Clin Invest. 2021. PMID: 33301427 Free PMC article.
Myc Dysregulation in Activated Macrophages Initiates Iron-Mediated Lipid Peroxidation that Fuels Type I Interferon and Compromises TB Resistance.
Yabaji SM, Zhernovkov V, Araveti PB, Lata S, Rukhlenko OS, Abdullatif SA, Alekseev Y, Ma Q, Dayama G, Lau NC, Bishai WR, Crossland NA, Campbell JD, Kholodenko BN, Gimelbrant AA, Kobzik L, Kramnik I. Yabaji SM, et al. Among authors: kobzik l. bioRxiv [Preprint]. 2024 Mar 10:2024.03.05.583602. doi: 10.1101/2024.03.05.583602. bioRxiv. 2024. PMID: 38496444 Free PMC article. Preprint.
296 results