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Cellular mechanotransduction relies on tension-induced and chaperone-assisted autophagy.
Ulbricht A, Eppler FJ, Tapia VE, van der Ven PF, Hampe N, Hersch N, Vakeel P, Stadel D, Haas A, Saftig P, Behrends C, Fürst DO, Volkmer R, Hoffmann B, Kolanus W, Höhfeld J. Ulbricht A, et al. Among authors: hohfeld j. Curr Biol. 2013 Mar 4;23(5):430-5. doi: 10.1016/j.cub.2013.01.064. Epub 2013 Feb 21. Curr Biol. 2013. PMID: 23434281 Free article.
Maintaining proteostasis under mechanical stress.
Höhfeld J, Benzing T, Bloch W, Fürst DO, Gehlert S, Hesse M, Hoffmann B, Hoppe T, Huesgen PF, Köhn M, Kolanus W, Merkel R, Niessen CM, Pokrzywa W, Rinschen MM, Wachten D, Warscheid B. Höhfeld J, et al. EMBO Rep. 2021 Aug 4;22(8):e52507. doi: 10.15252/embr.202152507. Epub 2021 Jul 26. EMBO Rep. 2021. PMID: 34309183 Free PMC article. Review.
The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1.
Kathage B, Gehlert S, Ulbricht A, Lüdecke L, Tapia VE, Orfanos Z, Wenzel D, Bloch W, Volkmer R, Fleischmann BK, Fürst DO, Höhfeld J. Kathage B, et al. Among authors: hohfeld j. Biochim Biophys Acta Mol Cell Res. 2017 Jan;1864(1):62-75. doi: 10.1016/j.bbamcr.2016.10.007. Epub 2016 Oct 15. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 27756573 Free article.
BAG3-mediated proteostasis at a glance.
Klimek C, Kathage B, Wördehoff J, Höhfeld J. Klimek C, et al. Among authors: hohfeld j. J Cell Sci. 2017 Sep 1;130(17):2781-2788. doi: 10.1242/jcs.203679. Epub 2017 Aug 14. J Cell Sci. 2017. PMID: 28808089 Review.
Tension-induced autophagy: may the chaperone be with you.
Ulbricht A, Höhfeld J. Ulbricht A, et al. Among authors: hohfeld j. Autophagy. 2013 Jun 1;9(6):920-2. doi: 10.4161/auto.24213. Epub 2013 Mar 21. Autophagy. 2013. PMID: 23518596 Free PMC article.
72 results