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A distinct ssDNA/RNA binding interface in the Nsp9 protein from SARS-CoV-2.
El-Kamand S, Du Plessis MD, Breen N, Johnson L, Beard S, Kwan AH, Richard DJ, Cubeddu L, Gamsjaeger R. El-Kamand S, et al. Among authors: richard dj. Proteins. 2022 Jan;90(1):176-185. doi: 10.1002/prot.26205. Epub 2021 Aug 13. Proteins. 2022. PMID: 34369011 Free PMC article.
Single-stranded DNA-binding protein hSSB1 is critical for genomic stability.
Richard DJ, Bolderson E, Cubeddu L, Wadsworth RI, Savage K, Sharma GG, Nicolette ML, Tsvetanov S, McIlwraith MJ, Pandita RK, Takeda S, Hay RT, Gautier J, West SC, Paull TT, Pandita TK, White MF, Khanna KK. Richard DJ, et al. Nature. 2008 May 29;453(7195):677-81. doi: 10.1038/nature06883. Epub 2008 Apr 30. Nature. 2008. PMID: 18449195
hSSB1 (NABP2/OBFC2B) is regulated by oxidative stress.
Paquet N, Adams MN, Ashton NW, Touma C, Gamsjaeger R, Cubeddu L, Leong V, Beard S, Bolderson E, Botting CH, O'Byrne KJ, Richard DJ. Paquet N, et al. Among authors: richard dj. Sci Rep. 2016 Jun 8;6:27446. doi: 10.1038/srep27446. Sci Rep. 2016. PMID: 27273218 Free PMC article.
A structural analysis of DNA binding by hSSB1 (NABP2/OBFC2B) in solution.
Touma C, Kariawasam R, Gimenez AX, Bernardo RE, Ashton NW, Adams MN, Paquet N, Croll TI, O'Byrne KJ, Richard DJ, Cubeddu L, Gamsjaeger R. Touma C, et al. Among authors: richard dj. Nucleic Acids Res. 2016 Sep 19;44(16):7963-73. doi: 10.1093/nar/gkw617. Epub 2016 Jul 7. Nucleic Acids Res. 2016. PMID: 27387285 Free PMC article.
148 results