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Increased mammalian lifespan and a segmental and tissue-specific slowing of aging after genetic reduction of mTOR expression.
Wu JJ, Liu J, Chen EB, Wang JJ, Cao L, Narayan N, Fergusson MM, Rovira II, Allen M, Springer DA, Lago CU, Zhang S, DuBois W, Ward T, deCabo R, Gavrilova O, Mock B, Finkel T. Wu JJ, et al. Among authors: rovira ii. Cell Rep. 2013 Sep 12;4(5):913-20. doi: 10.1016/j.celrep.2013.07.030. Epub 2013 Aug 29. Cell Rep. 2013. PMID: 23994476 Free PMC article.
Wnt signaling regulates hepatic metabolism.
Liu H, Fergusson MM, Wu JJ, Rovira II, Liu J, Gavrilova O, Lu T, Bao J, Han D, Sack MN, Finkel T. Liu H, et al. Among authors: rovira ii. Sci Signal. 2011 Feb 1;4(158):ra6. doi: 10.1126/scisignal.2001249. Sci Signal. 2011. PMID: 21285411 Free PMC article.
The In Vivo Biology of the Mitochondrial Calcium Uniporter.
Liu JC, Parks RJ, Liu J, Stares J, Rovira II, Murphy E, Finkel T. Liu JC, et al. Among authors: rovira ii. Adv Exp Med Biol. 2017;982:49-63. doi: 10.1007/978-3-319-55330-6_3. Adv Exp Med Biol. 2017. PMID: 28551781 Review.
The NAD-dependent deacetylase SIRT2 is required for programmed necrosis.
Narayan N, Lee IH, Borenstein R, Sun J, Wong R, Tong G, Fergusson MM, Liu J, Rovira II, Cheng HL, Wang G, Gucek M, Lombard D, Alt FW, Sack MN, Murphy E, Cao L, Finkel T. Narayan N, et al. Among authors: rovira ii. Nature. 2012 Dec 13;492(7428):199-204. doi: 10.1038/nature11700. Epub 2012 Nov 28. Nature. 2012. PMID: 23201684 Retracted.
Reciprocal regulation of acetyl-CoA carboxylase 1 and senescence in human fibroblasts involves oxidant mediated p38 MAPK activation.
Marmisolle I, Martínez J, Liu J, Mastrogiovanni M, Fergusson MM, Rovira II, Castro L, Trostchansky A, Moreno M, Cao L, Finkel T, Quijano C. Marmisolle I, et al. Among authors: rovira ii. Arch Biochem Biophys. 2017 Jan 1;613:12-22. doi: 10.1016/j.abb.2016.10.016. Epub 2016 Oct 27. Arch Biochem Biophys. 2017. PMID: 27983949 Free PMC article.
149 results