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Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion.
Markovic DS, Vinnakota K, Chirasani S, Synowitz M, Raguet H, Stock K, Sliwa M, Lehmann S, Kälin R, van Rooijen N, Holmbeck K, Heppner FL, Kiwit J, Matyash V, Lehnardt S, Kaminska B, Glass R, Kettenmann H. Markovic DS, et al. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12530-5. doi: 10.1073/pnas.0804273106. Epub 2009 Jul 15. Proc Natl Acad Sci U S A. 2009. PMID: 19617536 Free PMC article.
Wittig derivatization of sesquiterpenoid polygodial leads to cytostatic agents with activity against drug resistant cancer cells and capable of pyrrolylation of primary amines.
Dasari R, De Carvalho A, Medellin DC, Middleton KN, Hague F, Volmar MN, Frolova LV, Rossato MF, De La Chapa JJ, Dybdal-Hargreaves NF, Pillai A, Kälin RE, Mathieu V, Rogelj S, Gonzales CB, Calixto JB, Evidente A, Gautier M, Munirathinam G, Glass R, Burth P, Pelly SC, van Otterlo WA, Kiss R, Kornienko A. Dasari R, et al. Among authors: kalin re. Eur J Med Chem. 2015 Oct 20;103:226-37. doi: 10.1016/j.ejmech.2015.08.047. Epub 2015 Aug 29. Eur J Med Chem. 2015. PMID: 26360047 Free PMC article.
Monitoring of Tumor Growth with [(18)F]-FET PET in a Mouse Model of Glioblastoma: SUV Measurements and Volumetric Approaches.
Holzgreve A, Brendel M, Gu S, Carlsen J, Mille E, Böning G, Mastrella G, Unterrainer M, Gildehaus FJ, Rominger A, Bartenstein P, Kälin RE, Glass R, Albert NL. Holzgreve A, et al. Among authors: kalin re. Front Neurosci. 2016 Jun 14;10:260. doi: 10.3389/fnins.2016.00260. eCollection 2016. Front Neurosci. 2016. PMID: 27378835 Free PMC article.
Decreased demand for olfactory periglomerular cells impacts on neural precursor cell viability in the rostral migratory stream.
Langenfurth A, Gu S, Bautze V, Zhang C, Neumann JE, Schüller U, Stock K, Wolf SA, Maier AM, Mastrella G, Pak A, Cheng H, Kälin RE, Holmbeck K, Strotmann J, Kettenmann H, Glass R. Langenfurth A, et al. Among authors: kalin re. Sci Rep. 2016 Aug 30;6:32203. doi: 10.1038/srep32203. Sci Rep. 2016. PMID: 27573347 Free PMC article.
Targeting APLN/APLNR Improves Antiangiogenic Efficiency and Blunts Proinvasive Side Effects of VEGFA/VEGFR2 Blockade in Glioblastoma.
Mastrella G, Hou M, Li M, Stoecklein VM, Zdouc N, Volmar MNM, Miletic H, Reinhard S, Herold-Mende CC, Kleber S, Eisenhut K, Gargiulo G, Synowitz M, Vescovi AL, Harter PN, Penninger JM, Wagner E, Mittelbronn M, Bjerkvig R, Hambardzumyan D, Schüller U, Tonn JC, Radke J, Glass R, Kälin RE. Mastrella G, et al. Among authors: kalin re. Cancer Res. 2019 May 1;79(9):2298-2313. doi: 10.1158/0008-5472.CAN-18-0881. Epub 2019 Feb 4. Cancer Res. 2019. PMID: 30718358 Free article.
TAMEP are brain tumor parenchymal cells controlling neoplastic angiogenesis and progression.
Kälin RE, Cai L, Li Y, Zhao D, Zhang H, Cheng J, Zhang W, Wu Y, Eisenhut K, Janssen P, Schmitt L, Enard W, Michels F, Flüh C, Hou M, Kirchleitner SV, Siller S, Schiemann M, Andrä I, Montanez E, Giachino C, Taylor V, Synowitz M, Tonn JC, von Baumgarten L, Schulz C, Hellmann I, Glass R. Kälin RE, et al. Cell Syst. 2021 Mar 17;12(3):248-262.e7. doi: 10.1016/j.cels.2021.01.002. Epub 2021 Feb 15. Cell Syst. 2021. PMID: 33592194 Free article.
Cannabidiol converts NF-κB into a tumor suppressor in glioblastoma with defined antioxidative properties.
Volmar MNM, Cheng J, Alenezi H, Richter S, Haug A, Hassan Z, Goldberg M, Li Y, Hou M, Herold-Mende C, Maire CL, Lamszus K, Flüh C, Held-Feindt J, Gargiulo G, Topping GJ, Schilling F, Saur D, Schneider G, Synowitz M, Schick JA, Kälin RE, Glass R. Volmar MNM, et al. Among authors: kalin re. Neuro Oncol. 2021 Nov 2;23(11):1898-1910. doi: 10.1093/neuonc/noab095. Neuro Oncol. 2021. PMID: 33864076 Free PMC article.
32 results