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Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency.
Cong K, Peng M, Kousholt AN, Lee WTC, Lee S, Nayak S, Krais J, VanderVere-Carozza PS, Pawelczak KS, Calvo J, Panzarino NJ, Turchi JJ, Johnson N, Jonkers J, Rothenberg E, Cantor SB. Cong K, et al. Among authors: pawelczak ks. Mol Cell. 2021 Aug 5;81(15):3227. doi: 10.1016/j.molcel.2021.07.015. Mol Cell. 2021. PMID: 34358459 Free article. No abstract available.
DNA repair targeted therapy: The past or future of cancer treatment?
Gavande NS, VanderVere-Carozza PS, Hinshaw HD, Jalal SI, Sears CR, Pawelczak KS, Turchi JJ. Gavande NS, et al. Among authors: pawelczak ks. Pharmacol Ther. 2016 Apr;160:65-83. doi: 10.1016/j.pharmthera.2016.02.003. Epub 2016 Feb 16. Pharmacol Ther. 2016. PMID: 26896565 Free PMC article. Review.
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