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Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency.
Cong K, Peng M, Kousholt AN, Lee WTC, Lee S, Nayak S, Krais J, VanderVere-Carozza PS, Pawelczak KS, Calvo J, Panzarino NJ, Turchi JJ, Johnson N, Jonkers J, Rothenberg E, Cantor SB. Cong K, et al. Among authors: kousholt an. Mol Cell. 2021 Aug 5;81(15):3227. doi: 10.1016/j.molcel.2021.07.015. Mol Cell. 2021. PMID: 34358459 Free article. No abstract available.
Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency.
Cong K, Peng M, Kousholt AN, Lee WTC, Lee S, Nayak S, Krais J, VanderVere-Carozza PS, Pawelczak KS, Calvo J, Panzarino NJ, Turchi JJ, Johnson N, Jonkers J, Rothenberg E, Cantor SB. Cong K, et al. Among authors: kousholt an. Mol Cell. 2021 Aug 5;81(15):3128-3144.e7. doi: 10.1016/j.molcel.2021.06.011. Epub 2021 Jul 2. Mol Cell. 2021. PMID: 34216544 Free PMC article.
Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens.
Zhao Y, Tabet D, Rubio Contreras D, Lao L, Kousholt AN, Weile J, Melo H, Hoeg L, Feng S, Coté AG, Lin ZY, Setiaputra D, Jonkers J, Gingras AC, Gómez Herreros F, Roth FP, Durocher D. Zhao Y, et al. Among authors: kousholt an. Mol Cell. 2023 Aug 3;83(15):2792-2809.e9. doi: 10.1016/j.molcel.2023.06.025. Epub 2023 Jul 20. Mol Cell. 2023. PMID: 37478847 Free article.
Easy quantification of template-directed CRISPR/Cas9 editing.
Brinkman EK, Kousholt AN, Harmsen T, Leemans C, Chen T, Jonkers J, van Steensel B. Brinkman EK, et al. Among authors: kousholt an. Nucleic Acids Res. 2018 Jun 1;46(10):e58. doi: 10.1093/nar/gky164. Nucleic Acids Res. 2018. PMID: 29538768 Free PMC article.
H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours.
Dibitetto D, Liptay M, Vivalda F, Dogan H, Gogola E, González Fernández M, Duarte A, Schmid JA, Decollogny M, Francica P, Przetocka S, Durant ST, Forment JV, Klebic I, Siffert M, de Bruijn R, Kousholt AN, Marti NA, Dettwiler M, Sørensen CS, Tille JC, Undurraga M, Labidi-Galy I, Lopes M, Sartori AA, Jonkers J, Rottenberg S. Dibitetto D, et al. Among authors: kousholt an. Nat Commun. 2024 May 24;15(1):4430. doi: 10.1038/s41467-024-48715-1. Nat Commun. 2024. PMID: 38789420 Free PMC article.
FBH1 Catalyzes Regression of Stalled Replication Forks.
Fugger K, Mistrik M, Neelsen KJ, Yao Q, Zellweger R, Kousholt AN, Haahr P, Chu WK, Bartek J, Lopes M, Hickson ID, Sørensen CS. Fugger K, et al. Among authors: kousholt an. Cell Rep. 2015 Mar 17;10(10):1749-1757. doi: 10.1016/j.celrep.2015.02.028. Epub 2015 Mar 12. Cell Rep. 2015. PMID: 25772361 Free article.
17 results