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Dermonecrosis caused by a spitting cobra snakebite results from toxin potentiation and is prevented by the repurposed drug varespladib.
Bartlett KE, Hall SR, Rasmussen SA, Crittenden E, Dawson CA, Albulescu LO, Laprade W, Harrison RA, Saviola AJ, Modahl CM, Jenkins TP, Wilkinson MC, Gutiérrez JM, Casewell NR. Bartlett KE, et al. Among authors: jenkins tp. Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2315597121. doi: 10.1073/pnas.2315597121. Epub 2024 Apr 30. Proc Natl Acad Sci U S A. 2024. PMID: 38687786 Free PMC article.
Streamlining the Analysis of Proteins from Snake Venom.
Oganesyan I, Jenkins TP, Laustsen AH, Zenobi R, Harrison JA. Oganesyan I, et al. Among authors: jenkins tp. J Proteome Res. 2024 May 30. doi: 10.1021/acs.jproteome.4c00013. Online ahead of print. J Proteome Res. 2024. PMID: 38814071
Machine-learning guided Venom Induced Dermonecrosis Analysis tooL: VIDAL.
Laprade W, Bartlett KE, Christensen CR, Kazandjian TD, Patel RN, Crittenden E, Dawson CA, Mansourvar M, Wolff DS, Fryer T, Laustsen AH, Casewell NR, Gutiérrez JM, Hall SR, Jenkins TP. Laprade W, et al. Among authors: jenkins tp. Sci Rep. 2023 Dec 8;13(1):21662. doi: 10.1038/s41598-023-49011-6. Sci Rep. 2023. PMID: 38066189 Free PMC article.
Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes.
Ledsgaard L, Wade J, Jenkins TP, Boddum K, Oganesyan I, Harrison JA, Villar P, Leah RA, Zenobi R, Schoffelen S, Voldborg B, Ljungars A, McCafferty J, Lomonte B, Gutiérrez JM, Laustsen AH, Karatt-Vellatt A. Ledsgaard L, et al. Among authors: jenkins tp. Nat Commun. 2023 Feb 8;14(1):682. doi: 10.1038/s41467-023-36393-4. Nat Commun. 2023. PMID: 36755049 Free PMC article.
In vivo neutralization of coral snake venoms with an oligoclonal nanobody mixture in a murine challenge model.
Benard-Valle M, Wouters Y, Ljungars A, Nguyen GTT, Ahmadi S, Ebersole TW, Dahl CH, Guadarrama-Martínez A, Jeppesen F, Eriksen H, Rodríguez-Barrera G, Boddum K, Jenkins TP, Bjørn SP, Schoffelen S, Voldborg BG, Alagón A, Laustsen AH. Benard-Valle M, et al. Among authors: jenkins tp. Nat Commun. 2024 May 21;15(1):4310. doi: 10.1038/s41467-024-48539-z. Nat Commun. 2024. PMID: 38773068 Free PMC article.
60 results