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Discovery of the Selective Protein Kinase C-θ Kinase Inhibitor, CC-90005.
Papa P, Whitefield B, Mortensen DS, Cashion D, Huang D, Torres E, Parnes J, Sapienza J, Hansen J, Correa M, Delgado M, Harris R, Hegde S, Norris S, Bahmanyar S, Plantevin-Krenitsky V, Liu Z, Leftheris K, Kulkarni A, Bennett B, Hur EM, Ringheim G, Khambatta G, Chan H, Muir J, Blease K, Burnett K, LeBrun L, Morrison L, Celeridad M, Khattri R, Cathers BE. Papa P, et al. Among authors: norris s. J Med Chem. 2021 Aug 26;64(16):11886-11903. doi: 10.1021/acs.jmedchem.1c00388. Epub 2021 Aug 6. J Med Chem. 2021. PMID: 34355886
Discovery of the c-Jun N-Terminal Kinase Inhibitor CC-90001.
Nagy MA, Hilgraf R, Mortensen DS, Elsner J, Norris S, Tikhe J, Yoon W, Paisner D, Delgado M, Erdman P, Haelewyn J, Khambatta G, Xu L, Romanow WJ, Condroski K, Bahmanyar S, McCarrick M, Benish B, Blease K, LeBrun L, Moghaddam MF, Apuy J, Canan SS, Bennett BL, Satoh Y. Nagy MA, et al. Among authors: norris s. J Med Chem. 2021 Dec 23;64(24):18193-18208. doi: 10.1021/acs.jmedchem.1c01716. Epub 2021 Dec 13. J Med Chem. 2021. PMID: 34894681
Design and Synthesis of Novel Cereblon Binders for Use in Targeted Protein Degradation.
Norris S, Ba X, Rhodes J, Huang D, Khambatta G, Buenviaje J, Nayak S, Meiring J, Reiss S, Xu S, Shi L, Whitefield B, Alexander M, Horn EJ, Correa M, Tehrani L, Hansen JD, Papa P, Mortensen DS. Norris S, et al. J Med Chem. 2023 Dec 14;66(23):16388-16409. doi: 10.1021/acs.jmedchem.3c01848. Epub 2023 Nov 22. J Med Chem. 2023. PMID: 37991844
Selective non zinc binding inhibitors of MMP13.
De Savi C, Morley AD, Ting A, Nash I, Karabelas K, Wood CM, James M, Norris SJ, Karoutchi G, Rankine N, Hamlin G, Macfaul PA, Ryan D, Baker SV, Hargreaves D, Gerhardt S. De Savi C, et al. Among authors: norris sj. Bioorg Med Chem Lett. 2011 Jul 15;21(14):4215-9. doi: 10.1016/j.bmcl.2011.05.075. Epub 2011 May 27. Bioorg Med Chem Lett. 2011. PMID: 21669521
Variability of polygenic prediction for body mass index in Africa.
Chikowore T, Läll K, Micklesfield LK, Lombard Z, Goedecke JH, Fatumo S, Norris SA, Magi R, Ramsay M, Franks PW, Pare G, Morris AP. Chikowore T, et al. Among authors: norris sa. Genome Med. 2024 May 30;16(1):74. doi: 10.1186/s13073-024-01348-x. Genome Med. 2024. PMID: 38816834 Free PMC article.
Sex Differences in Dystonia.
Kilic-Berkmen G, Scorr LM, McKay L, Thayani M, Donsante Y, Perlmutter JS, Norris SA, Wright L, Klein C, Feuerstein JS, Mahajan A, Wagle-Shukla A, Malaty I, LeDoux MS, Pirio-Richardson S, Pantelyat A, Moukheiber E, Frank S, Ondo W, Saunders-Pullman R, Lohman K, Hess EJ, Jinnah HA. Kilic-Berkmen G, et al. Among authors: norris sa. Mov Disord Clin Pract. 2024 May 22. doi: 10.1002/mdc3.14059. Online ahead of print. Mov Disord Clin Pract. 2024. PMID: 38778444
Research priorities for the management of major trauma: an international priority setting partnership with the James Lind Alliance.
Bretherton CP, Hirst R, Gacaferi H, Gower J, Exell L, Johnston S, Martin S, Leech C, Hilton C, Battle C, Axelrod D, Vallier H, Van Embden D, Stockton DJ, Cole E, Williams J, Johnson L, Laubscher M, Webb M, Braude P, Norris S, Bell S, Maqungo S, Griffin XL; Major Trauma Priority Setting Partnership Steering Group. Bretherton CP, et al. Among authors: norris s. BMJ Open. 2024 May 15;14(5):e083450. doi: 10.1136/bmjopen-2023-083450. BMJ Open. 2024. PMID: 38754886 Free PMC article.
1,454 results