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Targeting Notch Inhibitors to the Myeloma Bone Marrow Niche Decreases Tumor Growth and Bone Destruction without Gut Toxicity.
Sabol HM, Ferrari AJ, Adhikari M, Amorim T, McAndrews K, Anderson J, Vigolo M, Lehal R, Cregor M, Khan S, Cuevas PL, Helms JA, Kurihara N, Srinivasan V, Ebetino FH, Boeckman RK Jr, Roodman GD, Bellido T, Delgado-Calle J. Sabol HM, et al. Among authors: ebetino fh. Cancer Res. 2021 Oct 1;81(19):5102-5114. doi: 10.1158/0008-5472.CAN-21-0524. Epub 2021 Aug 4. Cancer Res. 2021. PMID: 34348968 Free PMC article.
Targeting anti-cancer agents to bone using bisphosphonates.
Xing L, Ebetino FH, Boeckman RK Jr, Srinivasan V, Tao J, Sawyer TK, Li J, Yao Z, Boyce BF. Xing L, et al. Among authors: ebetino fh. Bone. 2020 Sep;138:115492. doi: 10.1016/j.bone.2020.115492. Epub 2020 Jun 23. Bone. 2020. PMID: 32585321 Free PMC article. Review.
Bisphosphonates for delivering drugs to bone.
Sun S, Tao J, Sedghizadeh PP, Cherian P, Junka AF, Sodagar E, Xing L, Boeckman RK Jr, Srinivasan V, Yao Z, Boyce BF, Lipe B, Neighbors JD, Russell RGG, McKenna CE, Ebetino FH. Sun S, et al. Among authors: ebetino fh. Br J Pharmacol. 2021 May;178(9):2008-2025. doi: 10.1111/bph.15251. Epub 2021 Apr 10. Br J Pharmacol. 2021. PMID: 32876338 Free PMC article. Review.
The Notch pathway regulates the bone gain induced by PTH anabolic signaling.
Delgado-Calle J, McAndrews K, Wu G, Orr AL, Ferrari A, Tu X, Srinivasan V, Roodman GD, Ebetino FH, Boeckman RK Jr, Bellido T. Delgado-Calle J, et al. Among authors: ebetino fh. FASEB J. 2022 Mar;36(3):e22196. doi: 10.1096/fj.202101807R. FASEB J. 2022. PMID: 35137455 Free PMC article.
102 results