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Insulin and IGF-1 receptors regulate complex I-dependent mitochondrial bioenergetics and supercomplexes via FoxOs in muscle.
Bhardwaj G, Penniman CM, Jena J, Suarez Beltran PA, Foster C, Poro K, Junck TL, Hinton AO Jr, Souvenir R, Fuqua JD, Morales PE, Bravo-Sagua R, Sivitz WI, Lira VA, Abel ED, O'Neill BT. Bhardwaj G, et al. Among authors: morales pe. J Clin Invest. 2021 Sep 15;131(18):e146415. doi: 10.1172/JCI146415. J Clin Invest. 2021. PMID: 34343133 Free PMC article.
Mitochondrial fragmentation impairs insulin-dependent glucose uptake by modulating Akt activity through mitochondrial Ca2+ uptake.
del Campo A, Parra V, Vásquez-Trincado C, Gutiérrez T, Morales PE, López-Crisosto C, Bravo-Sagua R, Navarro-Marquez MF, Verdejo HE, Contreras-Ferrat A, Troncoso R, Chiong M, Lavandero S. del Campo A, et al. Among authors: morales pe. Am J Physiol Endocrinol Metab. 2014 Jan 1;306(1):E1-E13. doi: 10.1152/ajpendo.00146.2013. Epub 2013 Oct 1. Am J Physiol Endocrinol Metab. 2014. PMID: 24085037 Free article.
[Mitochondrial dynamics: a potential new therapeutic target for heart failure].
Kuzmicic J, Del Campo A, López-Crisosto C, Morales PE, Pennanen C, Bravo-Sagua R, Hechenleitner J, Zepeda R, Castro PF, Verdejo HE, Parra V, Chiong M, Lavandero S. Kuzmicic J, et al. Among authors: morales pe. Rev Esp Cardiol. 2011 Oct;64(10):916-23. doi: 10.1016/j.recesp.2011.05.018. Epub 2011 Aug 5. Rev Esp Cardiol. 2011. PMID: 21820793 Free article. Review. Spanish.
Organelle communication: signaling crossroads between homeostasis and disease.
Bravo-Sagua R, Torrealba N, Paredes F, Morales PE, Pennanen C, López-Crisosto C, Troncoso R, Criollo A, Chiong M, Hill JA, Simmen T, Quest AF, Lavandero S. Bravo-Sagua R, et al. Among authors: morales pe. Int J Biochem Cell Biol. 2014 May;50:55-9. doi: 10.1016/j.biocel.2014.01.019. Epub 2014 Feb 15. Int J Biochem Cell Biol. 2014. PMID: 24534274 Review.
Herpud1 impacts insulin-dependent glucose uptake in skeletal muscle cells by controlling the Ca2+-calcineurin-Akt axis.
Navarro-Marquez M, Torrealba N, Troncoso R, Vásquez-Trincado C, Rodriguez M, Morales PE, Villalobos E, Eura Y, Garcia L, Chiong M, Klip A, Jaimovich E, Kokame K, Lavandero S. Navarro-Marquez M, et al. Among authors: morales pe. Biochim Biophys Acta Mol Basis Dis. 2018 May;1864(5 Pt A):1653-1662. doi: 10.1016/j.bbadis.2018.02.018. Epub 2018 Feb 24. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29486284 Free article.
Is Mitochondrial Dysfunction a Common Root of Noncommunicable Chronic Diseases?
Diaz-Vegas A, Sanchez-Aguilera P, Krycer JR, Morales PE, Monsalves-Alvarez M, Cifuentes M, Rothermel BA, Lavandero S. Diaz-Vegas A, et al. Among authors: morales pe. Endocr Rev. 2020 Jun 1;41(3):bnaa005. doi: 10.1210/endrev/bnaa005. Endocr Rev. 2020. PMID: 32179913 Free PMC article. Review.
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