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Insulin and IGF-1 receptors regulate complex I-dependent mitochondrial bioenergetics and supercomplexes via FoxOs in muscle.
Bhardwaj G, Penniman CM, Jena J, Suarez Beltran PA, Foster C, Poro K, Junck TL, Hinton AO Jr, Souvenir R, Fuqua JD, Morales PE, Bravo-Sagua R, Sivitz WI, Lira VA, Abel ED, O'Neill BT. Bhardwaj G, et al. Among authors: fuqua jd. J Clin Invest. 2021 Sep 15;131(18):e146415. doi: 10.1172/JCI146415. J Clin Invest. 2021. PMID: 34343133 Free PMC article.
Loss of FoxOs in muscle increases strength and mitochondrial function during aging.
Penniman CM, Bhardwaj G, Nowers CJ, Brown CU, Junck TL, Boyer CK, Jena J, Fuqua JD, Lira VA, O'Neill BT. Penniman CM, et al. Among authors: fuqua jd. J Cachexia Sarcopenia Muscle. 2023 Feb;14(1):243-259. doi: 10.1002/jcsm.13124. Epub 2022 Nov 28. J Cachexia Sarcopenia Muscle. 2023. PMID: 36442857 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35556377
Impaired proteostatic mechanisms other than decreased protein synthesis limit old skeletal muscle recovery after disuse atrophy.
Fuqua JD, Lawrence MM, Hettinger ZR, Borowik AK, Brecheen PL, Szczygiel MM, Abbott CB, Peelor FF 3rd, Confides AL, Kinter M, Bodine SC, Dupont-Versteegden EE, Miller BF. Fuqua JD, et al. J Cachexia Sarcopenia Muscle. 2023 Oct;14(5):2076-2089. doi: 10.1002/jcsm.13285. Epub 2023 Jul 14. J Cachexia Sarcopenia Muscle. 2023. PMID: 37448295 Free PMC article.