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SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8 T cells.
Minervina AA, Pogorelyy MV, Kirk AM, Crawford JC, Allen EK, Chou CH, Mettelman RC, Allison KJ, Lin CY, Brice DC, Zhu X, Vegesana K, Wu G, Trivedi S, Kottapalli P, Darnell D, McNeely S, Olsen SR, Schultz-Cherry S, Estepp JH; SJTRC Study Team; McGargill MA, Wolf J, Thomas PG. Minervina AA, et al. Among authors: thomas pg. medRxiv [Preprint]. 2022 Jan 26:2021.07.12.21260227. doi: 10.1101/2021.07.12.21260227. medRxiv. 2022. PMID: 34341799 Free PMC article. Updated. Preprint.
The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus.
Keating R, Hertz T, Wehenkel M, Harris TL, Edwards BA, McClaren JL, Brown SA, Surman S, Wilson ZS, Bradley P, Hurwitz J, Chi H, Doherty PC, Thomas PG, McGargill MA. Keating R, et al. Among authors: thomas pg. Nat Immunol. 2013 Dec;14(12):1266-76. doi: 10.1038/ni.2741. Epub 2013 Oct 20. Nat Immunol. 2013. PMID: 24141387 Free PMC article.
Detection of antibodies against Turkey astrovirus in humans.
Meliopoulos VA, Kayali G, Burnham A, Oshansky CM, Thomas PG, Gray GC, Beck MA, Schultz-Cherry S. Meliopoulos VA, et al. Among authors: thomas pg. PLoS One. 2014 May 14;9(5):e96934. doi: 10.1371/journal.pone.0096934. eCollection 2014. PLoS One. 2014. PMID: 24826893 Free PMC article.
Immunity to influenza. Preventing infection and regulating disease.
Allen EK, Thomas PG. Allen EK, et al. Among authors: thomas pg. Am J Respir Crit Care Med. 2015 Feb 1;191(3):248-51. doi: 10.1164/rccm.201412-2245ED. Am J Respir Crit Care Med. 2015. PMID: 25635487 Free PMC article. No abstract available.
Diverse heterologous primary infections radically alter immunodominance hierarchies and clinical outcomes following H7N9 influenza challenge in mice.
Duan S, Meliopoulos VA, McClaren JL, Guo XZ, Sanders CJ, Smallwood HS, Webby RJ, Schultz-Cherry SL, Doherty PC, Thomas PG. Duan S, et al. Among authors: thomas pg. PLoS Pathog. 2015 Feb 10;11(2):e1004642. doi: 10.1371/journal.ppat.1004642. eCollection 2015 Feb. PLoS Pathog. 2015. PMID: 25668410 Free PMC article.
Quantifiable predictive features define epitope-specific T cell receptor repertoires.
Dash P, Fiore-Gartland AJ, Hertz T, Wang GC, Sharma S, Souquette A, Crawford JC, Clemens EB, Nguyen THO, Kedzierska K, La Gruta NL, Bradley P, Thomas PG. Dash P, et al. Among authors: thomas pg. Nature. 2017 Jul 6;547(7661):89-93. doi: 10.1038/nature22383. Epub 2017 Jun 21. Nature. 2017. PMID: 28636592 Free PMC article.
VDJdb: a curated database of T-cell receptor sequences with known antigen specificity.
Shugay M, Bagaev DV, Zvyagin IV, Vroomans RM, Crawford JC, Dolton G, Komech EA, Sycheva AL, Koneva AE, Egorov ES, Eliseev AV, Van Dyk E, Dash P, Attaf M, Rius C, Ladell K, McLaren JE, Matthews KK, Clemens EB, Douek DC, Luciani F, van Baarle D, Kedzierska K, Kesmir C, Thomas PG, Price DA, Sewell AK, Chudakov DM. Shugay M, et al. Among authors: thomas pg. Nucleic Acids Res. 2018 Jan 4;46(D1):D419-D427. doi: 10.1093/nar/gkx760. Nucleic Acids Res. 2018. PMID: 28977646 Free PMC article.
Hitting the Target: How T Cells Detect and Eliminate Tumors.
Zamora AE, Crawford JC, Thomas PG. Zamora AE, et al. Among authors: thomas pg. J Immunol. 2018 Jan 15;200(2):392-399. doi: 10.4049/jimmunol.1701413. J Immunol. 2018. PMID: 29311380 Free PMC article. Review.
Clonally diverse CD38+HLA-DR+CD8+ T cells persist during fatal H7N9 disease.
Wang Z, Zhu L, Nguyen THO, Wan Y, Sant S, Quiñones-Parra SM, Crawford JC, Eltahla AA, Rizzetto S, Bull RA, Qiu C, Koutsakos M, Clemens EB, Loh L, Chen T, Liu L, Cao P, Ren Y, Kedzierski L, Kotsimbos T, McCaw JM, La Gruta NL, Turner SJ, Cheng AC, Luciani F, Zhang X, Doherty PC, Thomas PG, Xu J, Kedzierska K. Wang Z, et al. Among authors: thomas pg. Nat Commun. 2018 Feb 26;9(1):824. doi: 10.1038/s41467-018-03243-7. Nat Commun. 2018. PMID: 29483513 Free PMC article.
363 results