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Transgenic mice for in vivo epigenome editing with CRISPR-based systems.
Nat Methods. 2021 Aug;18(8):965-974. doi: 10.1038/s41592-021-01207-2. Epub 2021 Aug 2.
Nat Methods. 2021.
PMID: 34341582
Free PMC article.
Disruption of histone methylation in developing sperm impairs offspring health transgenerationally.
Siklenka K, Erkek S, Godmann M, Lambrot R, McGraw S, Lafleur C, Cohen T, Xia J, Suderman M, Hallett M, Trasler J, Peters AH, Kimmins S.
Siklenka K, et al.
Science. 2015 Nov 6;350(6261):aab2006. doi: 10.1126/science.aab2006. Epub 2015 Oct 8.
Science. 2015.
PMID: 26449473
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The genomic distribution of histone H3K4me2 in spermatogonia is highly conserved in sperm†.
Lambrot R, Siklenka K, Lafleur C, Kimmins S.
Lambrot R, et al. Among authors: siklenka k.
Biol Reprod. 2019 Jun 1;100(6):1661-1672. doi: 10.1093/biolre/ioz055.
Biol Reprod. 2019.
PMID: 30951591
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Sperm histone H3 lysine 4 trimethylation is altered in a genetic mouse model of transgenerational epigenetic inheritance.
Lismer A, Siklenka K, Lafleur C, Dumeaux V, Kimmins S.
Lismer A, et al. Among authors: siklenka k.
Nucleic Acids Res. 2020 Nov 18;48(20):11380-11393. doi: 10.1093/nar/gkaa712.
Nucleic Acids Res. 2020.
PMID: 33068438
Free PMC article.
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miRNet - dissecting miRNA-target interactions and functional associations through network-based visual analysis.
Fan Y, Siklenka K, Arora SK, Ribeiro P, Kimmins S, Xia J.
Fan Y, et al. Among authors: siklenka k.
Nucleic Acids Res. 2016 Jul 8;44(W1):W135-41. doi: 10.1093/nar/gkw288. Epub 2016 Apr 21.
Nucleic Acids Res. 2016.
PMID: 27105848
Free PMC article.
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Multicenter integrated analysis of noncoding CRISPRi screens.
Yao D, Tycko J, Oh JW, Bounds LR, Gosai SJ, Lataniotis L, Mackay-Smith A, Doughty BR, Gabdank I, Schmidt H, Guerrero-Altamirano T, Siklenka K, Guo K, White AD, Youngworth I, Andreeva K, Ren X, Barrera A, Luo Y, Yardımcı GG, Tewhey R, Kundaje A, Greenleaf WJ, Sabeti PC, Leslie C, Pritykin Y, Moore JE, Beer MA, Gersbach CA, Reddy TE, Shen Y, Engreitz JM, Bassik MC, Reilly SK.
Yao D, et al. Among authors: siklenka k.
Nat Methods. 2024 Apr;21(4):723-734. doi: 10.1038/s41592-024-02216-7. Epub 2024 Mar 19.
Nat Methods. 2024.
PMID: 38504114
Free PMC article.
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Transcriptional and epigenetic regulators of human CD8+ T cell function identified through orthogonal CRISPR screens.
McCutcheon SR, Swartz AM, Brown MC, Barrera A, McRoberts Amador C, Siklenka K, Humayun L, Ter Weele MA, Isaacs JM, Reddy TE, Allen AS, Nair SK, Antonia SJ, Gersbach CA.
McCutcheon SR, et al. Among authors: siklenka k.
Nat Genet. 2023 Dec;55(12):2211-2223. doi: 10.1038/s41588-023-01554-0. Epub 2023 Nov 9.
Nat Genet. 2023.
PMID: 37945901
Free PMC article.
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Orthogonal CRISPR screens to identify transcriptional and epigenetic regulators of human CD8 T cell function.
McCutcheon SR, Swartz AM, Brown MC, Barrera A, Amador CM, Siklenka K, Humayun L, Isaacs JM, Reddy TE, Nair S, Antonia S, Gersbach CA.
McCutcheon SR, et al. Among authors: siklenka k.
bioRxiv [Preprint]. 2023 May 1:2023.05.01.538906. doi: 10.1101/2023.05.01.538906.
bioRxiv. 2023.
PMID: 37205457
Free PMC article.
Updated.
Preprint.
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