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Analysis of Prostate Cancer Tumor Microenvironment Identifies Reduced Stromal CD4 Effector T-cell Infiltration in Tumors with Pelvic Nodal Metastasis.
Eur Urol Open Sci. 2021 May 25;29:19-29. doi: 10.1016/j.euros.2021.05.001. eCollection 2021 Jul.
Eur Urol Open Sci. 2021.
PMID: 34337530
Free PMC article.
Automated Co-in Situ Hybridization and Immunofluorescence Using Archival Tumor Tissue.
Officer LK, Andreou KE, Teodósio AV, He Z, Le Quesne JP.
Officer LK, et al. Among authors: teodosio av.
Methods Mol Biol. 2020;2148:245-256. doi: 10.1007/978-1-0716-0623-0_16.
Methods Mol Biol. 2020.
PMID: 32394387
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SOX9 has distinct roles in the formation and progression of different non-small cell lung cancer histotypes.
Bao J, Närhi K, Teodòsio A, Hemmes A, Linnavirta NM, Mäyränpää MI, Salmenkivi K, Le Quesne J, Verschuren EW.
Bao J, et al.
J Pathol. 2021 Sep;255(1):16-29. doi: 10.1002/path.5733. Epub 2021 Jun 19.
J Pathol. 2021.
PMID: 34021911
Free article.
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MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression.
Knight JRP, Alexandrou C, Skalka GL, Vlahov N, Pennel K, Officer L, Teodosio A, Kanellos G, Gay DM, May-Wilson S, Smith EM, Najumudeen AK, Gilroy K, Ridgway RA, Flanagan DJ, Smith RCL, McDonald L, MacKay C, Cheasty A, McArthur K, Stanway E, Leach JD, Jackstadt R, Waldron JA, Campbell AD, Vlachogiannis G, Valeri N, Haigis KM, Sonenberg N, Proud CG, Jones NP, Swarbrick ME, McKinnon HJ, Faller WJ, Le Quesne J, Edwards J, Willis AE, Bushell M, Sansom OJ.
Knight JRP, et al.
Cancer Discov. 2021 May;11(5):1228-1247. doi: 10.1158/2159-8290.CD-20-0652. Epub 2020 Dec 16.
Cancer Discov. 2021.
PMID: 33328217
Free PMC article.
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The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer.
Ghaddar N, Wang S, Woodvine B, Krishnamoorthy J, van Hoef V, Darini C, Kazimierczak U, Ah-Son N, Popper H, Johnson M, Officer L, Teodósio A, Broggini M, Mann KK, Hatzoglou M, Topisirovic I, Larsson O, Le Quesne J, Koromilas AE.
Ghaddar N, et al.
Nat Commun. 2021 Jul 30;12(1):4651. doi: 10.1038/s41467-021-24661-0.
Nat Commun. 2021.
PMID: 34330898
Free PMC article.
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The pathogenesis of mesothelioma is driven by a dysregulated translatome.
Grosso S, Marini A, Gyuraszova K, Voorde JV, Sfakianos A, Garland GD, Tenor AR, Mordue R, Chernova T, Morone N, Sereno M, Smith CP, Officer L, Farahmand P, Rooney C, Sumpton D, Das M, Teodósio A, Ficken C, Martin MG, Spriggs RV, Sun XM, Bushell M, Sansom OJ, Murphy D, MacFarlane M, Le Quesne JPC, Willis AE.
Grosso S, et al.
Nat Commun. 2021 Aug 13;12(1):4920. doi: 10.1038/s41467-021-25173-7.
Nat Commun. 2021.
PMID: 34389715
Free PMC article.
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Neuropathological findings in two patients with fatal COVID-19.
Jensen MP, Le Quesne J, Officer-Jones L, Teodòsio A, Thaventhiran J, Ficken C, Goddard M, Smith C, Menon D, Allinson KSJ.
Jensen MP, et al.
Neuropathol Appl Neurobiol. 2021 Feb;47(1):17-25. doi: 10.1111/nan.12662. Epub 2020 Sep 24.
Neuropathol Appl Neurobiol. 2021.
PMID: 32895961
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Unbiased cell surface proteomics identifies SEMA4A as an effective immunotherapy target for myeloma.
Anderson GSF, Ballester-Beltran J, Giotopoulos G, Guerrero JA, Surget S, Williamson JC, So T, Bloxham D, Aubareda A, Asby R, Walker I, Jenkinson L, Soilleux EJ, Roy JP, Teodósio A, Ficken C, Officer-Jones L, Nasser S, Skerget S, Keats JJ, Greaves P, Tai YT, Anderson KC, MacFarlane M, Thaventhiran JE, Huntly BJP, Lehner PJ, Chapman MA.
Anderson GSF, et al.
Blood. 2022 Apr 21;139(16):2471-2482. doi: 10.1182/blood.2021015161.
Blood. 2022.
PMID: 35134130
Free PMC article.
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