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Cardiovascular outcomes with sodium-glucose cotransporter-2 inhibitors vs other glucose-lowering drugs in 13 countries across three continents: analysis of CVD-REAL data.
Khunti K, Kosiborod M, Kim DJ, Kohsaka S, Lam CSP, Goh SY, Chiang CE, Shaw JE, Cavender MA, Tangri N, Franch-Nadal J, Holl RW, Jørgensen ME, Norhammar A, Eriksson JG, Zaccardi F, Karasik A, Magliano DJ, Thuresson M, Chen H, Wittbrodt E, Bodegård J, Surmont F, Fenici P; CVD-REAL Investigators and Study Group. Khunti K, et al. Among authors: chen h. Cardiovasc Diabetol. 2021 Jul 31;20(1):159. doi: 10.1186/s12933-021-01345-z. Cardiovasc Diabetol. 2021. PMID: 34332558 Free PMC article.
Treatment patterns and associated factors in 14 668 people with type 2 diabetes initiating a second-line therapy: Results from the global DISCOVER study programme.
Nicolucci A, Charbonnel B, Gomes MB, Khunti K, Kosiborod M, Shestakova MV, Shimomura I, Watada H, Chen H, Cid-Ruzafa J, Fenici P, Hammar N, Surmont F, Tang F, Pocock S. Nicolucci A, et al. Among authors: chen h. Diabetes Obes Metab. 2019 Nov;21(11):2474-2485. doi: 10.1111/dom.13830. Epub 2019 Aug 5. Diabetes Obes Metab. 2019. PMID: 31297947 Free PMC article.
Glycaemic control in patients with type 2 diabetes initiating second-line therapy: Results from the global DISCOVER study programme.
Khunti K, Chen H, Cid-Ruzafa J, Fenici P, Gomes MB, Hammar N, Ji L, Kosiborod M, Pocock S, Shestakova MV, Shimomura I, Tang F, Watada H, Nicolucci A; DISCOVER investigators. Khunti K, et al. Among authors: chen h. Diabetes Obes Metab. 2020 Jan;22(1):66-78. doi: 10.1111/dom.13866. Epub 2019 Oct 1. Diabetes Obes Metab. 2020. PMID: 31468637 Free PMC article.
Socioeconomic factors associated with hypoglycaemia in patients starting second-line glucose-lowering therapy: The DISCOVER study.
Rathmann W, Charbonnel B, Gomes MB, Hammar N, Khunti K, Kosiborod M, Kuss O, Shestakova MV, Watada H, Shimomura I, Tang F, Cid-Ruzafa J, Chen H, Fenici P, Surmont F, Ji L; DISCOVER investigators. Rathmann W, et al. Among authors: chen h. Diabetes Res Clin Pract. 2020 Jul;165:108250. doi: 10.1016/j.diabres.2020.108250. Epub 2020 Jun 10. Diabetes Res Clin Pract. 2020. PMID: 32531326
Risk of cardiovascular events and death associated with initiation of SGLT2 inhibitors compared with DPP-4 inhibitors: an analysis from the CVD-REAL 2 multinational cohort study.
Kohsaka S, Lam CSP, Kim DJ, Cavender MA, Norhammar A, Jørgensen ME, Birkeland KI, Holl RW, Franch-Nadal J, Tangri N, Shaw JE, Ilomäki J, Karasik A, Goh SY, Chiang CE, Thuresson M, Chen H, Wittbrodt E, Bodegård J, Surmont F, Fenici P, Kosiborod M; CVD-REAL 2 Investigators and Study Group. Kohsaka S, et al. Among authors: chen h. Lancet Diabetes Endocrinol. 2020 Jul;8(7):606-615. doi: 10.1016/S2213-8587(20)30130-3. Lancet Diabetes Endocrinol. 2020. PMID: 32559476
Global patterns of comprehensive cardiovascular risk factor control in patients with type 2 diabetes mellitus: Insights from the DISCOVER study.
Patel KK, Gomes MB, Charbonnel B, Chen H, Cid-Ruzafa J, Fenici P, Hammar N, Ji L, Kennedy KF, Khunti K, Kosiborod M, Pocock S, Shestakova MV, Shimomura I, Surmont F, Watada H, Arnold SV. Patel KK, et al. Among authors: chen h. Diabetes Obes Metab. 2021 Jan;23(1):39-48. doi: 10.1111/dom.14180. Epub 2020 Sep 22. Diabetes Obes Metab. 2021. PMID: 32845558 Free PMC article.
Metformin discontinuation in patients beginning second-line glucose-lowering therapy: results from the global observational DISCOVER study programme.
Khunti K, Gomes MB, Kosiborod M, Nicolucci A, Pocock S, Rathmann W, Shestakova MV, Shimomura I, Watada H, Chen H, Cid-Ruzafa J, Fenici P, Hammar N, Tang F, Ji L; DISCOVER Scientific Committee and all DISCOVER investigators. Khunti K, et al. Among authors: chen h. BMJ Open. 2020 Aug 30;10(8):e034613. doi: 10.1136/bmjopen-2019-034613. BMJ Open. 2020. PMID: 32868349 Free PMC article.
Type 2 diabetes and heart failure: insights from the global DISCOVER study.
Arnold SV, Khunti K, Bonnet F, Charbonnel B, Chen H, Cid-Ruzafa J, Cooper A, Fenici P, Gomes MB, Hammar N, Ji L, Luporini-Saraiva G, Medina J, Nicolucci A, Ramirez L, Shestakova MV, Shimomura I, Surmont F, Tang F, Vora J, Watada H, Kosiborod M; DISCOVER investigators. Arnold SV, et al. Among authors: chen h. ESC Heart Fail. 2021 Apr;8(2):1711-1716. doi: 10.1002/ehf2.13235. Epub 2021 Feb 11. ESC Heart Fail. 2021. PMID: 33570253 Free PMC article.
Association of sodium-glucose cotransporter-2 inhibitors with outcomes in type 2 diabetes with reduced and preserved left ventricular ejection fraction: Analysis from the CVD-REAL 2 study.
Lam CSP, Karasik A, Melzer-Cohen C, Cavender MA, Kohsaka S, Norhammar A, Thuresson M, Chen H, Wittbrodt E, Fenici P, Kosiborod M; CVD-REAL Investigators and Study Group. Lam CSP, et al. Among authors: chen h. Diabetes Obes Metab. 2021 Jun;23(6):1431-1435. doi: 10.1111/dom.14356. Epub 2021 Mar 23. Diabetes Obes Metab. 2021. PMID: 33606906 Free PMC article.
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