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Autoantibodies against NMDA receptor 1 modify rather than cause encephalitis.
Wilke JBH, Hindermann M, Berghoff SA, Zihsler S, Arinrad S, Ronnenberg A, Barnkothe N, Steixner-Kumar AA, Röglin S, Stöcker W, Hollmann M, Nave KA, Lühder F, Ehrenreich H. Wilke JBH, et al. Among authors: hollmann m. Mol Psychiatry. 2021 Dec;26(12):7746-7759. doi: 10.1038/s41380-021-01238-3. Epub 2021 Jul 30. Mol Psychiatry. 2021. PMID: 34331009 Free PMC article.
Uncoupling the widespread occurrence of anti-NMDAR1 autoantibodies from neuropsychiatric disease in a novel autoimmune model.
Pan H, Oliveira B, Saher G, Dere E, Tapken D, Mitjans M, Seidel J, Wesolowski J, Wakhloo D, Klein-Schmidt C, Ronnenberg A, Schwabe K, Trippe R, Mätz-Rensing K, Berghoff S, Al-Krinawe Y, Martens H, Begemann M, Stöcker W, Kaup FJ, Mischke R, Boretius S, Nave KA, Krauss JK, Hollmann M, Lühder F, Ehrenreich H. Pan H, et al. Among authors: hollmann m. Mol Psychiatry. 2019 Oct;24(10):1489-1501. doi: 10.1038/s41380-017-0011-3. Epub 2018 Feb 9. Mol Psychiatry. 2019. PMID: 29426955 Free PMC article.
NMDAR1 autoantibodies amplify behavioral phenotypes of genetic white matter inflammation: a mild encephalitis model with neuropsychiatric relevance.
Arinrad S, Wilke JBH, Seelbach A, Doeren J, Hindermann M, Butt UJ, Steixner-Kumar AA, Spieth L, Ronnenberg A, Pan H, Berghoff SA, Hollmann M, Lühder F, Nave KA, Bechter K, Ehrenreich H. Arinrad S, et al. Among authors: hollmann m. Mol Psychiatry. 2022 Dec;27(12):4974-4983. doi: 10.1038/s41380-021-01392-8. Epub 2021 Dec 6. Mol Psychiatry. 2022. PMID: 34866134 Free PMC article.
Multiple inducers and novel roles of autoantibodies against the obligatory NMDAR subunit NR1: a translational study from chronic life stress to brain injury.
Pan H, Steixner-Kumar AA, Seelbach A, Deutsch N, Ronnenberg A, Tapken D, von Ahsen N, Mitjans M, Worthmann H, Trippe R, Klein-Schmidt C, Schopf N, Rentzsch K, Begemann M, Wienands J, Stöcker W, Weissenborn K, Hollmann M, Nave KA, Lühder F, Ehrenreich H. Pan H, et al. Among authors: hollmann m. Mol Psychiatry. 2021 Jun;26(6):2471-2482. doi: 10.1038/s41380-020-0672-1. Epub 2020 Feb 24. Mol Psychiatry. 2021. PMID: 32089545 Free PMC article.
All naturally occurring autoantibodies against the NMDA receptor subunit NR1 have pathogenic potential irrespective of epitope and immunoglobulin class.
Castillo-Gómez E, Oliveira B, Tapken D, Bertrand S, Klein-Schmidt C, Pan H, Zafeiriou P, Steiner J, Jurek B, Trippe R, Prüss H, Zimmermann WH, Bertrand D, Ehrenreich H, Hollmann M. Castillo-Gómez E, et al. Among authors: hollmann m. Mol Psychiatry. 2017 Dec;22(12):1776-1784. doi: 10.1038/mp.2016.125. Epub 2016 Aug 9. Mol Psychiatry. 2017. PMID: 27502473
816 results