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Selective Inhibition of JAK1 Primes STAT5-Driven Human Leukemia Cells for ATRA-Induced Differentiation.
Ramsey HE, Stengel K, Pino JC, Johnston G, Childress M, Gorska AE, Arrate PM, Fuller L, Villaume M, Fischer MA, Ferrell PB Jr, Roe CE, Zou J, Lubbock ALR, Stubbs M, Zinkel S, Irish JM, Lopez CF, Hiebert S, Savona MR. Ramsey HE, et al. Among authors: fischer ma. Target Oncol. 2021 Sep;16(5):663-674. doi: 10.1007/s11523-021-00830-5. Epub 2021 Jul 29. Target Oncol. 2021. PMID: 34324169 Free PMC article.
Mtg16/Eto2 contributes to murine T-cell development.
Hunt A, Fischer M, Engel ME, Hiebert SW. Hunt A, et al. Mol Cell Biol. 2011 Jul;31(13):2544-51. doi: 10.1128/MCB.01458-10. Epub 2011 May 2. Mol Cell Biol. 2011. PMID: 21536648 Free PMC article.
HDAC3 is essential for DNA replication in hematopoietic progenitor cells.
Summers AR, Fischer MA, Stengel KR, Zhao Y, Kaiser JF, Wells CE, Hunt A, Bhaskara S, Luzwick JW, Sampathi S, Chen X, Thompson MA, Cortez D, Hiebert SW. Summers AR, et al. Among authors: fischer ma. J Clin Invest. 2013 Jul;123(7):3112-23. doi: 10.1172/JCI60806. Epub 2013 Jun 10. J Clin Invest. 2013. PMID: 23921131 Free PMC article.
High-Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML.
Zhao Y, Liu Q, Acharya P, Stengel KR, Sheng Q, Zhou X, Kwak H, Fischer MA, Bradner JE, Strickland SA, Mohan SR, Savona MR, Venters BJ, Zhou MM, Lis JT, Hiebert SW. Zhao Y, et al. Among authors: fischer ma. Cell Rep. 2016 Aug 16;16(7):2003-16. doi: 10.1016/j.celrep.2016.07.032. Epub 2016 Aug 4. Cell Rep. 2016. PMID: 27498870 Free PMC article.
Discovery and biological characterization of potent myeloid cell leukemia-1 inhibitors.
Lee T, Bian Z, Zhao B, Hogdal LJ, Sensintaffar JL, Goodwin CM, Belmar J, Shaw S, Tarr JC, Veerasamy N, Matulis SM, Koss B, Fischer MA, Arnold AL, Camper DV, Browning CF, Rossanese OW, Budhraja A, Opferman J, Boise LH, Savona MR, Letai A, Olejniczak ET, Fesik SW. Lee T, et al. Among authors: fischer ma. FEBS Lett. 2017 Jan;591(1):240-251. doi: 10.1002/1873-3468.12497. Epub 2016 Dec 19. FEBS Lett. 2017. PMID: 27878989 Free PMC article.
BET inhibitors reduce cell size and induce reversible cell cycle arrest in AML.
Zhang S, Zhao Y, Heaster TM, Fischer MA, Stengel KR, Zhou X, Ramsey H, Zhou MM, Savona MR, Skala MC, Hiebert SW. Zhang S, et al. Among authors: fischer ma. J Cell Biochem. 2019 May;120(5):7309-7322. doi: 10.1002/jcb.28005. Epub 2018 Nov 11. J Cell Biochem. 2019. PMID: 30417424 Free PMC article.
403 results