Leppert PC - Search Results

1

Extracellular matrix and Hippo signaling as therapeutic targets of antifibrotic compounds for uterine fibroids.

Islam MS, Afrin S, Singh B, Jayes FL, Brennan JT, Borahay MA, Leppert PC, Segars JH. Islam MS, et al. Among authors: leppert pc. Clin Transl Med. 2021 Jul;11(7):e475. doi: 10.1002/ctm2.475. Clin Transl Med. 2021. PMID: 34323413 Free PMC article. Clinical Trial.

2

A Phase I Clinical Trial to Assess Safety and Tolerability of Injectable Collagenase in Women with Symptomatic Uterine Fibroids.

Singh B, Sims H, Trueheart I, Simpson K, Wang KC, Patzkowsky K, Wegman T, Soma JM, Dixon R, Jayes F, Voegltine K, Yenokyan G, Su SC, Leppert P, Segars JH. Singh B, et al. Reprod Sci. 2021 Sep;28(9):2699-2709. doi: 10.1007/s43032-021-00573-8. Epub 2021 Apr 29. Reprod Sci. 2021. PMID: 33914296 Free PMC article. Clinical Trial.

3

The extracellular matrix contributes to mechanotransduction in uterine fibroids.

Leppert PC, Jayes FL, Segars JH. Leppert PC, et al. Obstet Gynecol Int. 2014;2014:783289. doi: 10.1155/2014/783289. Epub 2014 Jul 3. Obstet Gynecol Int. 2014. PMID: 25110476 Free PMC article. Review.

4

Injectable Clostridium histolyticum collagenase as a potential treatment for uterine fibroids.

Brunengraber LN, Jayes FL, Leppert PC. Brunengraber LN, et al. Among authors: leppert pc. Reprod Sci. 2014 Dec;21(12):1452-9. doi: 10.1177/1933719114553449. Epub 2014 Oct 20. Reprod Sci. 2014. PMID: 25332216 Free PMC article.

5

Recent scientific advances in leiomyoma (uterine fibroids) research facilitates better understanding and management.

Taylor DK, Holthouser K, Segars JH, Leppert PC. Taylor DK, et al. Among authors: leppert pc. F1000Res. 2015 Jul 6;4(F1000 Faculty Rev):183. doi: 10.12688/f1000research.6189.1. eCollection 2015. F1000Res. 2015. PMID: 26236472 Free PMC article. Review.

6

Loss of stiffness in collagen-rich uterine fibroids after digestion with purified collagenase Clostridium histolyticum.

Jayes FL, Liu B, Moutos FT, Kuchibhatla M, Guilak F, Leppert PC. Jayes FL, et al. Among authors: leppert pc. Am J Obstet Gynecol. 2016 Nov;215(5):596.e1-596.e8. doi: 10.1016/j.ajog.2016.05.006. Epub 2016 May 10. Am J Obstet Gynecol. 2016. PMID: 27177523

7

Mechanical Signaling and Extracellular Matrix in Uterine Fibroids.

Rafique S, Segars JH, Leppert PC. Rafique S, et al. Among authors: leppert pc. Semin Reprod Med. 2017 Nov;35(6):487-493. doi: 10.1055/s-0037-1607268. Epub 2017 Nov 3. Semin Reprod Med. 2017. PMID: 29100236 Review. No abstract available.

8

Evidence of biomechanical and collagen heterogeneity in uterine fibroids.

Jayes FL, Liu B, Feng L, Aviles-Espinoza N, Leikin S, Leppert PC. Jayes FL, et al. Among authors: leppert pc. PLoS One. 2019 Apr 29;14(4):e0215646. doi: 10.1371/journal.pone.0215646. eCollection 2019. PLoS One. 2019. PMID: 31034494 Free PMC article.

9

Summary of the Proceedings of the Basic Science of Uterine Fibroids Meeting: New Developments February 28, 2020.

Leppert PC, Al-Hendy A, Baird DD, Bulun S, Catherino W, Dixon D, Ducharme M, Harmon QE, Jayes FL, Paul E, Perucho AM, Segars J, Simón C, Stewart EA, Teixeira J, Tinelli A, Tschumperlin D, Zota AR. Leppert PC, et al. F S Sci. 2021 Feb;2(1):88-100. doi: 10.1016/j.xfss.2020.11.001. Epub 2020 Nov 7. F S Sci. 2021. PMID: 34124698 Free PMC article.

10

Transforming growth factor beta3 regulates the versican variants in the extracellular matrix-rich uterine leiomyomas.

Norian JM, Malik M, Parker CY, Joseph D, Leppert PC, Segars JH, Catherino WH. Norian JM, et al. Among authors: leppert pc. Reprod Sci. 2009 Dec;16(12):1153-64. doi: 10.1177/1933719109343310. Epub 2009 Aug 21. Reprod Sci. 2009. PMID: 19700613 Free PMC article.

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