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Design and synthesis of novel conformationally constrained 7,12-dihydrodibenzo[b,h][1,6] naphthyridine and 7H-Chromeno[3,2-c] quinoline derivatives as topoisomerase I inhibitors: In vitro screening, molecular docking and ADME predictions.
Bioorg Chem. 2021 Oct;115:105174. doi: 10.1016/j.bioorg.2021.105174. Epub 2021 Jul 16.
Bioorg Chem. 2021.
PMID: 34314913
Novel quinoline and naphthalene derivatives as potent antimycobacterial agents.
Upadhayaya RS, Vandavasi JK, Kardile RA, Lahore SV, Dixit SS, Deokar HS, Shinde PD, Sarmah MP, Chattopadhyaya J.
Upadhayaya RS, et al. Among authors: kardile ra.
Eur J Med Chem. 2010 May;45(5):1854-67. doi: 10.1016/j.ejmech.2010.01.024. Epub 2010 Jan 20.
Eur J Med Chem. 2010.
PMID: 20137835
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Synthesis and antimycobacterial activity of prodrugs of indeno[2,1-c]quinoline derivatives.
Upadhayaya RS, Shinde PD, Kadam SA, Bawane AN, Sayyed AY, Kardile RA, Gitay PN, Lahore SV, Dixit SS, Földesi A, Chattopadhyaya J.
Upadhayaya RS, et al. Among authors: kardile ra.
Eur J Med Chem. 2011 Apr;46(4):1306-24. doi: 10.1016/j.ejmech.2011.01.053. Epub 2011 Feb 3.
Eur J Med Chem. 2011.
PMID: 21334792
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Design, synthesis, and biological evaluation of novel quinoline derivatives as small molecule mutant EGFR inhibitors targeting resistance in NSCLC: In vitro screening and ADME predictions.
Kardile RA, Sarkate AP, Lokwani DK, Tiwari SV, Azad R, Thopate SR.
Kardile RA, et al.
Eur J Med Chem. 2023 Jan 5;245(Pt 1):114889. doi: 10.1016/j.ejmech.2022.114889. Epub 2022 Oct 29.
Eur J Med Chem. 2023.
PMID: 36375337
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Carba-LNA-5MeC/A/G/T modified oligos show nucleobase-specific modulation of 3'-exonuclease activity, thermodynamic stability, RNA selectivity, and RNase H elicitation: synthesis and biochemistry.
Upadhayaya R, Deshpande SG, Li Q, Kardile RA, Sayyed AY, Kshirsagar EK, Salunke RV, Dixit SS, Zhou C, Földesi A, Chattopadhyaya J.
Upadhayaya R, et al. Among authors: kardile ra.
J Org Chem. 2011 Jun 3;76(11):4408-31. doi: 10.1021/jo200073q. Epub 2011 May 4.
J Org Chem. 2011.
PMID: 21500818
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