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Alpha-synuclein research: defining strategic moves in the battle against Parkinson's disease.
Oliveira LMA, Gasser T, Edwards R, Zweckstetter M, Melki R, Stefanis L, Lashuel HA, Sulzer D, Vekrellis K, Halliday GM, Tomlinson JJ, Schlossmacher M, Jensen PH, Schulze-Hentrich J, Riess O, Hirst WD, El-Agnaf O, Mollenhauer B, Lansbury P, Outeiro TF. Oliveira LMA, et al. Among authors: outeiro tf. NPJ Parkinsons Dis. 2021 Jul 26;7(1):65. doi: 10.1038/s41531-021-00203-9. NPJ Parkinsons Dis. 2021. PMID: 34312398 Free PMC article. Review.
Direct quantification of CSF alpha-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration.
Mollenhauer B, Cullen V, Kahn I, Krastins B, Outeiro TF, Pepivani I, Ng J, Schulz-Schaeffer W, Kretzschmar HA, McLean PJ, Trenkwalder C, Sarracino DA, Vonsattel JP, Locascio JJ, El-Agnaf OM, Schlossmacher MG. Mollenhauer B, et al. Among authors: outeiro tf. Exp Neurol. 2008 Oct;213(2):315-25. doi: 10.1016/j.expneurol.2008.06.004. Epub 2008 Jun 14. Exp Neurol. 2008. PMID: 18625222
Dopamine-induced conformational changes in alpha-synuclein.
Outeiro TF, Klucken J, Bercury K, Tetzlaff J, Putcha P, Oliveira LM, Quintas A, McLean PJ, Hyman BT. Outeiro TF, et al. PLoS One. 2009 Sep 4;4(9):e6906. doi: 10.1371/journal.pone.0006906. PLoS One. 2009. PMID: 19730729 Free PMC article.
β-synuclein aggregates and induces neurodegeneration in dopaminergic neurons.
Taschenberger G, Toloe J, Tereshchenko J, Akerboom J, Wales P, Benz R, Becker S, Outeiro TF, Looger LL, Bähr M, Zweckstetter M, Kügler S. Taschenberger G, et al. Among authors: outeiro tf. Ann Neurol. 2013 Jul;74(1):109-18. doi: 10.1002/ana.23905. Epub 2013 Aug 6. Ann Neurol. 2013. PMID: 23536356
α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner.
Yin G, Lopes da Fonseca T, Eisbach SE, Anduaga AM, Breda C, Orcellet ML, Szegő ÉM, Guerreiro P, Lázaro DF, Braus GH, Fernandez CO, Griesinger C, Becker S, Goody RS, Itzen A, Giorgini F, Outeiro TF, Zweckstetter M. Yin G, et al. Among authors: outeiro tf. Neurobiol Dis. 2014 Oct;70:149-61. doi: 10.1016/j.nbd.2014.06.018. Epub 2014 Jun 28. Neurobiol Dis. 2014. PMID: 24983211
329 results