Shearn CT - Search Results

1

NF-κB Regulation of LRH-1 and ABCG5/8 Potentiates Phytosterol Role in the Pathogenesis of Parenteral Nutrition-Associated Cholestasis.

Ghosh S, Devereaux MW, Anderson AL, Gehrke S, Reisz JA, D'Alessandro A, Orlicky DJ, Lovell M, El Kasmi KC, Shearn CT, Sokol RJ. Ghosh S, et al. Among authors: shearn ct. Hepatology. 2021 Dec;74(6):3284-3300. doi: 10.1002/hep.32071. Epub 2021 Aug 27. Hepatology. 2021. PMID: 34310734 Free PMC article.

2

Oxidative Stress and the ER Stress Response in a Murine Model for Early-Stage Alcoholic Liver Disease.

Galligan JJ, Smathers RL, Shearn CT, Fritz KS, Backos DS, Jiang H, Franklin CC, Orlicky DJ, Maclean KN, Petersen DR. Galligan JJ, et al. Among authors: shearn ct. J Toxicol. 2012;2012:207594. doi: 10.1155/2012/207594. Epub 2012 Jul 5. J Toxicol. 2012. PMID: 22829816 Free PMC article.

3

Susceptibility of L-FABP-/- mice to oxidative stress in early-stage alcoholic liver.

Smathers RL, Galligan JJ, Shearn CT, Fritz KS, Mercer K, Ronis M, Orlicky DJ, Davidson NO, Petersen DR. Smathers RL, et al. Among authors: shearn ct. J Lipid Res. 2013 May;54(5):1335-45. doi: 10.1194/jlr.M034892. Epub 2013 Jan 28. J Lipid Res. 2013. PMID: 23359610 Free PMC article.

4

Increased dietary fat contributes to dysregulation of the LKB1/AMPK pathway and increased damage in a mouse model of early-stage ethanol-mediated steatosis.

Shearn CT, Smathers RL, Jiang H, Orlicky DJ, Maclean KN, Petersen DR. Shearn CT, et al. J Nutr Biochem. 2013 Aug;24(8):1436-45. doi: 10.1016/j.jnutbio.2012.12.002. Epub 2013 Mar 1. J Nutr Biochem. 2013. PMID: 23465594 Free PMC article.

5

Increased carbonylation of the lipid phosphatase PTEN contributes to Akt2 activation in a murine model of early alcohol-induced steatosis.

Shearn CT, Smathers RL, Backos DS, Reigan P, Orlicky DJ, Petersen DR. Shearn CT, et al. Free Radic Biol Med. 2013 Dec;65:680-692. doi: 10.1016/j.freeradbiomed.2013.07.011. Epub 2013 Jul 17. Free Radic Biol Med. 2013. PMID: 23872024 Free PMC article.

6

Identification of 5' AMP-activated kinase as a target of reactive aldehydes during chronic ingestion of high concentrations of ethanol.

Shearn CT, Backos DS, Orlicky DJ, Smathers-McCullough RL, Petersen DR. Shearn CT, et al. J Biol Chem. 2014 May 30;289(22):15449-62. doi: 10.1074/jbc.M113.543942. Epub 2014 Apr 10. J Biol Chem. 2014. PMID: 24722988 Free PMC article.

7

Short term feeding of a high fat diet exerts an additive effect on hepatocellular damage and steatosis in liver-specific PTEN knockout mice.

Shearn CT, Mercer KE, Orlicky DJ, Hennings L, Smathers-McCullough RL, Stiles BL, Ronis MJ, Petersen DR. Shearn CT, et al. PLoS One. 2014 May 12;9(5):e96553. doi: 10.1371/journal.pone.0096553. eCollection 2014. PLoS One. 2014. PMID: 24818992 Free PMC article.

8

Increased 4-hydroxynonenal protein adducts in male GSTA4-4/PPAR-α double knockout mice enhance injury during early stages of alcoholic liver disease.

Ronis MJ, Mercer KE, Gannon B, Engi B, Zimniak P, Shearn CT, Orlicky DJ, Albano E, Badger TM, Petersen DR. Ronis MJ, et al. Among authors: shearn ct. Am J Physiol Gastrointest Liver Physiol. 2015 Mar 1;308(5):G403-15. doi: 10.1152/ajpgi.00154.2014. Epub 2014 Dec 11. Am J Physiol Gastrointest Liver Physiol. 2015. PMID: 25501545 Free PMC article.

9

Chronic ethanol consumption induces mitochondrial protein acetylation and oxidative stress in the kidney.

Harris PS, Roy SR, Coughlan C, Orlicky DJ, Liang Y, Shearn CT, Roede JR, Fritz KS. Harris PS, et al. Among authors: shearn ct. Redox Biol. 2015 Dec;6:33-40. doi: 10.1016/j.redox.2015.06.021. Epub 2015 Jul 6. Redox Biol. 2015. PMID: 26177469 Free PMC article.

10

Increased hepatocellular protein carbonylation in human end-stage alcoholic cirrhosis.

Shearn CT, Orlicky DJ, Saba LM, Shearn AH, Petersen DR. Shearn CT, et al. Among authors: shearn ah. Free Radic Biol Med. 2015 Dec;89:1144-53. doi: 10.1016/j.freeradbiomed.2015.10.420. Epub 2015 Oct 27. Free Radic Biol Med. 2015. PMID: 26518673 Free PMC article.

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