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SAMHD1 in cancer: curse or cure?
Schott K, Majer C, Bulashevska A, Childs L, Schmidt MHH, Rajalingam K, Munder M, König R. Schott K, et al. Among authors: konig r. J Mol Med (Berl). 2022 Mar;100(3):351-372. doi: 10.1007/s00109-021-02131-w. Epub 2021 Sep 4. J Mol Med (Berl). 2022. PMID: 34480199 Free PMC article. Review.
SAMHD1-deficient CD14+ cells from individuals with Aicardi-Goutières syndrome are highly susceptible to HIV-1 infection.
Berger A, Sommer AF, Zwarg J, Hamdorf M, Welzel K, Esly N, Panitz S, Reuter A, Ramos I, Jatiani A, Mulder LC, Fernandez-Sesma A, Rutsch F, Simon V, König R, Flory E. Berger A, et al. Among authors: konig r. PLoS Pathog. 2011 Dec;7(12):e1002425. doi: 10.1371/journal.ppat.1002425. Epub 2011 Dec 8. PLoS Pathog. 2011. PMID: 22174685 Free PMC article.
SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.
Baldauf HM, Pan X, Erikson E, Schmidt S, Daddacha W, Burggraf M, Schenkova K, Ambiel I, Wabnitz G, Gramberg T, Panitz S, Flory E, Landau NR, Sertel S, Rutsch F, Lasitschka F, Kim B, König R, Fackler OT, Keppler OT. Baldauf HM, et al. Among authors: konig r. Nat Med. 2012 Nov;18(11):1682-7. doi: 10.1038/nm.2964. Nat Med. 2012. PMID: 22972397 Free PMC article.
Restrictive influence of SAMHD1 on Hepatitis B Virus life cycle.
Sommer AF, Rivière L, Qu B, Schott K, Riess M, Ni Y, Shepard C, Schnellbächer E, Finkernagel M, Himmelsbach K, Welzel K, Kettern N, Donnerhak C, Münk C, Flory E, Liese J, Kim B, Urban S, König R. Sommer AF, et al. Among authors: konig r. Sci Rep. 2016 May 27;6:26616. doi: 10.1038/srep26616. Sci Rep. 2016. PMID: 27229711 Free PMC article.
Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells.
Baldauf HM, Stegmann L, Schwarz SM, Ambiel I, Trotard M, Martin M, Burggraf M, Lenzi GM, Lejk H, Pan X, Fregoso OI, Lim ES, Abraham L, Nguyen LA, Rutsch F, König R, Kim B, Emerman M, Fackler OT, Keppler OT. Baldauf HM, et al. Among authors: konig r. Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2729-2734. doi: 10.1073/pnas.1613635114. Epub 2017 Feb 22. Proc Natl Acad Sci U S A. 2017. PMID: 28228523 Free PMC article.
Role of Innate Genes in HIV Replication.
Schott K, Riess M, König R. Schott K, et al. Among authors: konig r. Curr Top Microbiol Immunol. 2018;419:69-111. doi: 10.1007/82_2017_29. Curr Top Microbiol Immunol. 2018. PMID: 28685292 Review.
USP18 (UBP43) Abrogates p21-Mediated Inhibition of HIV-1.
Osei Kuffour E, Schott K, Jaguva Vasudevan AA, Holler J, Schulz WA, Lang PA, Lang KS, Kim B, Häussinger D, König R, Münk C. Osei Kuffour E, et al. Among authors: konig r. J Virol. 2018 Sep 26;92(20):e00592-18. doi: 10.1128/JVI.00592-18. Print 2018 Oct 15. J Virol. 2018. PMID: 30068654 Free PMC article.
537 results