Holden-Dye L - Search Results

1

Development of emodepside as a possible adulticidal treatment for human onchocerciasis-The fruit of a successful industrial-academic collaboration.

Krücken J, Holden-Dye L, Keiser J, Prichard RK, Townson S, Makepeace BL, Hübner MP, Hahnel SR, Scandale I, Harder A, Kulke D. Krücken J, et al. Among authors: holden dye l. PLoS Pathog. 2021 Jul 22;17(7):e1009682. doi: 10.1371/journal.ppat.1009682. eCollection 2021 Jul. PLoS Pathog. 2021. PMID: 34293063 Free PMC article. Review.

2

The effect of the anthelmintic emodepside at the neuromuscular junction of the parasitic nematode Ascaris suum.

Willson J, Amliwala K, Harder A, Holden-Dye L, Walker RJ. Willson J, et al. Parasitology. 2003 Jan;126(Pt 1):79-86. doi: 10.1017/s0031182002002639. Parasitology. 2003. PMID: 12613766

3

Cyclooctadepsipeptides--an anthelmintically active class of compounds exhibiting a novel mode of action.

Harder A, Schmitt-Wrede HP, Krücken J, Marinovski P, Wunderlich F, Willson J, Amliwala K, Holden-Dye L, Walker R. Harder A, et al. Int J Antimicrob Agents. 2003 Sep;22(3):318-31. doi: 10.1016/s0924-8579(03)00219-x. Int J Antimicrob Agents. 2003. PMID: 13678839 Review.

4

Latrotoxin receptor signaling engages the UNC-13-dependent vesicle-priming pathway in C. elegans.

Willson J, Amliwala K, Davis A, Cook A, Cuttle MF, Kriek N, Hopper NA, O'Connor V, Harder A, Walker RJ, Holden-Dye L. Willson J, et al. Curr Biol. 2004 Aug 10;14(15):1374-9. doi: 10.1016/j.cub.2004.07.056. Curr Biol. 2004. PMID: 15296755 Free article.

5

Mechanisms of action of emodepside.

Harder A, Holden-Dye L, Walker R, Wunderlich F. Harder A, et al. Parasitol Res. 2005 Oct;97 Suppl 1:S1-S10. doi: 10.1007/s00436-005-1438-z. Parasitol Res. 2005. PMID: 16228263

6

Effects of the novel anthelmintic emodepside on the locomotion, egg-laying behaviour and development of Caenorhabditis elegans.

Bull K, Cook A, Hopper NA, Harder A, Holden-Dye L, Walker RJ. Bull K, et al. Int J Parasitol. 2007 May;37(6):627-36. doi: 10.1016/j.ijpara.2006.10.013. Epub 2006 Nov 27. Int J Parasitol. 2007. PMID: 17157854

7

The calcium-activated potassium channel, SLO-1, is required for the action of the novel cyclo-octadepsipeptide anthelmintic, emodepside, in Caenorhabditis elegans.

Guest M, Bull K, Walker RJ, Amliwala K, O'Connor V, Harder A, Holden-Dye L, Hopper NA. Guest M, et al. Int J Parasitol. 2007 Dec;37(14):1577-88. doi: 10.1016/j.ijpara.2007.05.006. Epub 2007 May 21. Int J Parasitol. 2007. PMID: 17583712

8

SLO, SLO, quick, quick, slow: calcium-activated potassium channels as regulators of Caenorhabditis elegans behaviour and targets for anthelmintics.

Holden-Dye L, O'Connor V, Hopper NA, Walker RJ, Harder A, Bull K, Guest M. Holden-Dye L, et al. Invert Neurosci. 2007 Dec;7(4):199-208. doi: 10.1007/s10158-007-0057-z. Epub 2007 Oct 26. Invert Neurosci. 2007. PMID: 17962986 Review.

9

Selective toxicity of the anthelmintic emodepside revealed by heterologous expression of human KCNMA1 in Caenorhabditis elegans.

Crisford A, Murray C, O'Connor V, Edwards RJ, Kruger N, Welz C, von Samson-Himmelstjerna G, Harder A, Walker RJ, Holden-Dye L. Crisford A, et al. Mol Pharmacol. 2011 Jun;79(6):1031-43. doi: 10.1124/mol.111.071043. Epub 2011 Mar 17. Mol Pharmacol. 2011. PMID: 21415309 Free PMC article.

10

SLO-1-channels of parasitic nematodes reconstitute locomotor behaviour and emodepside sensitivity in Caenorhabditis elegans slo-1 loss of function mutants.

Welz C, Krüger N, Schniederjans M, Miltsch SM, Krücken J, Guest M, Holden-Dye L, Harder A, von Samson-Himmelstjerna G. Welz C, et al. PLoS Pathog. 2011 Apr;7(4):e1001330. doi: 10.1371/journal.ppat.1001330. Epub 2011 Apr 7. PLoS Pathog. 2011. PMID: 21490955 Free PMC article.

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