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HOTAIR, a cell cycle-associated long noncoding RNA and a strong predictor of survival, is preferentially expressed in classical and mesenchymal glioma.
Zhang JX, Han L, Bao ZS, Wang YY, Chen LY, Yan W, Yu SZ, Pu PY, Liu N, You YP, Jiang T, Kang CS; Chinese Glioma Cooperative Group. Zhang JX, et al. Among authors: chen ly. Neuro Oncol. 2013 Dec;15(12):1595-603. doi: 10.1093/neuonc/not131. Epub 2013 Nov 7. Neuro Oncol. 2013. PMID: 24203894 Free PMC article.
HOTAIR is a therapeutic target in glioblastoma.
Zhou X, Ren Y, Zhang J, Zhang C, Zhang K, Han L, Kong L, Wei J, Chen L, Yang J, Wang Q, Zhang J, Yang Y, Jiang T, Li M, Kang C. Zhou X, et al. Among authors: chen l. Oncotarget. 2015 Apr 10;6(10):8353-65. doi: 10.18632/oncotarget.3229. Oncotarget. 2015. PMID: 25823657 Free PMC article.
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