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Amphiphilic anti-SARS-CoV-2 drug remdesivir incorporates into the lipid bilayer and nerve terminal membranes influencing excitatory and inhibitory neurotransmission.
Krisanova N, Pozdnyakova N, Pastukhov A, Dudarenko M, Shatursky O, Gnatyuk O, Afonina U, Pyrshev K, Dovbeshko G, Yesylevskyy S, Borisova T. Krisanova N, et al. Among authors: pyrshev k. Biochim Biophys Acta Biomembr. 2022 Aug 1;1864(8):183945. doi: 10.1016/j.bbamem.2022.183945. Epub 2022 Apr 22. Biochim Biophys Acta Biomembr. 2022. PMID: 35461828 Free PMC article.
Dual benefit of combined neuroprotection: Cholesterol depletion restores membrane microviscosity but not lipid order and enhances neuroprotective action of hypothermia in rat cortex nerve terminals.
Pastukhov A, Krisanova N, Pyrshev K, Borisova T. Pastukhov A, et al. Among authors: pyrshev k. Biochim Biophys Acta Biomembr. 2020 Sep 1;1862(9):183362. doi: 10.1016/j.bbamem.2020.183362. Epub 2020 May 21. Biochim Biophys Acta Biomembr. 2020. PMID: 32445746 Free article.
Apoptosis and eryptosis: Striking differences on biomembrane level.
Pyrshev KA, Klymchenko AS, Csúcs G, Demchenko AP. Pyrshev KA, et al. Biochim Biophys Acta Biomembr. 2018 Jun;1860(6):1362-1371. doi: 10.1016/j.bbamem.2018.03.019. Epub 2018 Mar 22. Biochim Biophys Acta Biomembr. 2018. PMID: 29573990 Free article.
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