Kale S - Search Results

1

Picomole-Scale Synthesis and Screening of Macrocyclic Compound Libraries by Acoustic Liquid Transfer.

Sangouard G, Zorzi A, Wu Y, Ehret E, Schüttel M, Kale S, Díaz-Perlas C, Vesin J, Bortoli Chapalay J, Turcatti G, Heinis C. Sangouard G, et al. Among authors: kale s. Angew Chem Int Ed Engl. 2021 Sep 27;60(40):21702-21707. doi: 10.1002/anie.202107815. Epub 2021 Aug 25. Angew Chem Int Ed Engl. 2021. PMID: 34268864

2

Thiol-to-amine cyclization reaction enables screening of large libraries of macrocyclic compounds and the generation of sub-kilodalton ligands.

Kale SS, Bergeron-Brlek M, Wu Y, Kumar MG, Pham MV, Bortoli J, Vesin J, Kong XD, Machado JF, Deyle K, Gonschorek P, Turcatti G, Cendron L, Angelini A, Heinis C. Kale SS, et al. Sci Adv. 2019 Aug 21;5(8):eaaw2851. doi: 10.1126/sciadv.aaw2851. eCollection 2019 Aug. Sci Adv. 2019. PMID: 31457083 Free PMC article.

3

Cyclization of peptides with two chemical bridges affords large scaffold diversities.

Kale SS, Villequey C, Kong XD, Zorzi A, Deyle K, Heinis C. Kale SS, et al. Nat Chem. 2018 Jul;10(7):715-723. doi: 10.1038/s41557-018-0042-7. Epub 2018 Apr 30. Nat Chem. 2018. PMID: 29713035

4

Macrocycle synthesis strategy based on step-wise "adding and reacting" three components enables screening of large combinatorial libraries.

Mothukuri GK, Kale SS, Stenbratt CL, Zorzi A, Vesin J, Bortoli Chapalay J, Deyle K, Turcatti G, Cendron L, Angelini A, Heinis C. Mothukuri GK, et al. Among authors: kale ss. Chem Sci. 2020 Jun 26;11(30):7858-7863. doi: 10.1039/d0sc01944e. Chem Sci. 2020. PMID: 34094158 Free PMC article.

5

Polar Hinges as Functionalized Conformational Constraints in (Bi)cyclic Peptides.

van de Langemheen H, Korotkovs V, Bijl J, Wilson C, Kale SS, Heinis C, Liskamp RM. van de Langemheen H, et al. Among authors: kale ss. Chembiochem. 2017 Feb 16;18(4):387-395. doi: 10.1002/cbic.201600612. Epub 2017 Jan 16. Chembiochem. 2017. PMID: 27982494

6

Conformational modulation of Ant-Pro oligomers using chirality alteration of proline residues.

Kale SS, Kotmale AS, Dutta AK, Pal S, Rajamohanan PR, Sanjayan GJ. Kale SS, et al. Org Biomol Chem. 2012 Nov 14;10(42):8426-33. doi: 10.1039/c2ob26132d. Epub 2012 Sep 24. Org Biomol Chem. 2012. PMID: 23001178

7

Orthanilic acid-promoted reverse turn formation in peptides.

Kale SS, Priya G, Kotmale AS, Gawade RL, Puranik VG, Rajamohanan PR, Sanjayan GJ. Kale SS, et al. Chem Commun (Camb). 2013 Mar 18;49(22):2222-4. doi: 10.1039/c3cc40522b. Chem Commun (Camb). 2013. PMID: 23392615

8

Bicyclic amino acid-carbohydrate-conjugates as conformationally restricted hydroxyethylamine (HEA) transition-state isosteres.

Kale SS, Chavan ST, Sabharwal SG, Puranik VG, Sanjayan GJ. Kale SS, et al. Org Biomol Chem. 2011 Nov 7;9(21):7300-2. doi: 10.1039/c1ob06215h. Epub 2011 Sep 14. Org Biomol Chem. 2011. PMID: 21915421

9

Carboxamide versus sulfonamide in peptide backbone folding: a case study with a hetero foldamer.

Ramesh VV, Kale SS, Kotmale AS, Gawade RL, Puranik VG, Rajamohanan PR, Sanjayan GJ. Ramesh VV, et al. Among authors: kale ss. Org Lett. 2013 Apr 5;15(7):1504-7. doi: 10.1021/ol4002762. Epub 2013 Mar 8. Org Lett. 2013. PMID: 23473041

10

Sequence-specific unusual (1-->2)-type helical turns in alpha/beta-hybrid peptides.

Prabhakaran P, Kale SS, Puranik VG, Rajamohanan PR, Chetina O, Howard JA, Hofmann HJ, Sanjayan GJ. Prabhakaran P, et al. Among authors: kale ss. J Am Chem Soc. 2008 Dec 31;130(52):17743-54. doi: 10.1021/ja804297f. J Am Chem Soc. 2008. PMID: 19061328

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