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Peptide ligands stabilized by small molecules.
Chen S, Bertoldo D, Angelini A, Pojer F, Heinis C. Chen S, et al. Among authors: heinis c. Angew Chem Int Ed Engl. 2014 Feb 3;53(6):1602-6. doi: 10.1002/anie.201309459. Epub 2014 Jan 22. Angew Chem Int Ed Engl. 2014. PMID: 24453110
Cyclic peptide therapeutics: past, present and future.
Zorzi A, Deyle K, Heinis C. Zorzi A, et al. Among authors: heinis c. Curr Opin Chem Biol. 2017 Jun;38:24-29. doi: 10.1016/j.cbpa.2017.02.006. Epub 2017 Feb 27. Curr Opin Chem Biol. 2017. PMID: 28249193 Review.
Thiol-to-amine cyclization reaction enables screening of large libraries of macrocyclic compounds and the generation of sub-kilodalton ligands.
Kale SS, Bergeron-Brlek M, Wu Y, Kumar MG, Pham MV, Bortoli J, Vesin J, Kong XD, Machado JF, Deyle K, Gonschorek P, Turcatti G, Cendron L, Angelini A, Heinis C. Kale SS, et al. Among authors: heinis c. Sci Adv. 2019 Aug 21;5(8):eaaw2851. doi: 10.1126/sciadv.aaw2851. eCollection 2019 Aug. Sci Adv. 2019. PMID: 31457083 Free PMC article.
91 results