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Picomole-Scale Synthesis and Screening of Macrocyclic Compound Libraries by Acoustic Liquid Transfer.
Angew Chem Int Ed Engl. 2021 Sep 27;60(40):21702-21707. doi: 10.1002/anie.202107815. Epub 2021 Aug 25.
Angew Chem Int Ed Engl. 2021.
PMID: 34268864
Synthesis and direct assay of large macrocycle diversities by combinatorial late-stage modification at picomole scale.
Habeshian S, Merz ML, Sangouard G, Mothukuri GK, Schüttel M, Bognár Z, Díaz-Perlas C, Vesin J, Bortoli Chapalay J, Turcatti G, Cendron L, Angelini A, Heinis C.
Habeshian S, et al. Among authors: bortoli chapalay j.
Nat Commun. 2022 Jul 2;13(1):3823. doi: 10.1038/s41467-022-31428-8.
Nat Commun. 2022.
PMID: 35780129
Free PMC article.
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Macrocycle synthesis strategy based on step-wise "adding and reacting" three components enables screening of large combinatorial libraries.
Mothukuri GK, Kale SS, Stenbratt CL, Zorzi A, Vesin J, Bortoli Chapalay J, Deyle K, Turcatti G, Cendron L, Angelini A, Heinis C.
Mothukuri GK, et al. Among authors: bortoli chapalay j.
Chem Sci. 2020 Jun 26;11(30):7858-7863. doi: 10.1039/d0sc01944e.
Chem Sci. 2020.
PMID: 34094158
Free PMC article.
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An optimized and validated 384-well plate assay to test platelet function in a high-throughput screening format.
Martins Lima A, Bragina ME, Burri O, Bortoli Chapalay J, Costa-Fraga FP, Chambon M, Fraga-Silva RA, Stergiopulos N.
Martins Lima A, et al. Among authors: bortoli chapalay j.
Platelets. 2019;30(5):563-571. doi: 10.1080/09537104.2018.1514106. Epub 2018 Sep 5.
Platelets. 2019.
PMID: 30183501
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