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Dose Rationale for Favipiravir Use in Patients Infected With SARS-CoV-2.
Eloy P, Solas C, Touret F, Mentré F, Malvy D, de Lamballerie X, Guedj J. Eloy P, et al. Among authors: solas c. Clin Pharmacol Ther. 2020 Aug;108(2):188. doi: 10.1002/cpt.1877. Epub 2020 May 21. Clin Pharmacol Ther. 2020. PMID: 32350860 No abstract available.
Concerns about pharmacokinetic (PK) and pharmacokinetic-pharmacodynamic (PK-PD) studies in the new therapeutic area of COVID-19 infection.
Venisse N, Peytavin G, Bouchet S, Gagnieu MC, Garraffo R, Guilhaumou R, Solas C; ANRS-AC43 Clinical Pharmacology Committee, SFPT Therapeutic Drug Monitoring and Treatment Personalization group. Venisse N, et al. Among authors: solas c. Antiviral Res. 2020 Sep;181:104866. doi: 10.1016/j.antiviral.2020.104866. Epub 2020 Jul 10. Antiviral Res. 2020. PMID: 32659293 Free PMC article. Review.
Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates.
Maisonnasse P, Guedj J, Contreras V, Behillil S, Solas C, Marlin R, Naninck T, Pizzorno A, Lemaitre J, Gonçalves A, Kahlaoui N, Terrier O, Fang RHT, Enouf V, Dereuddre-Bosquet N, Brisebarre A, Touret F, Chapon C, Hoen B, Lina B, Calatrava MR, van der Werf S, de Lamballerie X, Le Grand R. Maisonnasse P, et al. Among authors: solas c. Nature. 2020 Sep;585(7826):584-587. doi: 10.1038/s41586-020-2558-4. Epub 2020 Jul 22. Nature. 2020. PMID: 32698191
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity.
Kaptein SJF, Jacobs S, Langendries L, Seldeslachts L, Ter Horst S, Liesenborghs L, Hens B, Vergote V, Heylen E, Barthelemy K, Maas E, De Keyzer C, Bervoets L, Rymenants J, Van Buyten T, Zhang X, Abdelnabi R, Pang J, Williams R, Thibaut HJ, Dallmeier K, Boudewijns R, Wouters J, Augustijns P, Verougstraete N, Cawthorne C, Breuer J, Solas C, Weynand B, Annaert P, Spriet I, Vande Velde G, Neyts J, Rocha-Pereira J, Delang L. Kaptein SJF, et al. Among authors: solas c. Proc Natl Acad Sci U S A. 2020 Oct 27;117(43):26955-26965. doi: 10.1073/pnas.2014441117. Epub 2020 Oct 9. Proc Natl Acad Sci U S A. 2020. PMID: 33037151 Free PMC article.
Development and Validation of a Simple and Rapid Ultrahigh-Performance Liquid Chromatography Tandem Spectrometry Method for the Quantification of Hydroxychloroquine in Plasma and Blood Samples in the Emergency Context of SARS-CoV-2 Pandemic.
Doudka N, Giocanti M, Basso M, Ugdonne R, Barthelemy K, Lacarelle B, Blin O, Solas C, Guilhaumou R. Doudka N, et al. Among authors: solas c. Ther Drug Monit. 2021 Aug 1;43(4):570-576. doi: 10.1097/FTD.0000000000000836. Ther Drug Monit. 2021. PMID: 33165216 Free PMC article.
SARS-CoV-2 viral dynamics in non-human primates.
Gonçalves A, Maisonnasse P, Donati F, Albert M, Behillil S, Contreras V, Naninck T, Marlin R, Solas C, Pizzorno A, Lemaitre J, Kahlaoui N, Terrier O, Ho Tsong Fang R, Enouf V, Dereuddre-Bosquet N, Brisebarre A, Touret F, Chapon C, Hoen B, Lina B, Rosa Calatrava M, de Lamballerie X, Mentré F, Le Grand R, van der Werf S, Guedj J. Gonçalves A, et al. Among authors: solas c. PLoS Comput Biol. 2021 Mar 17;17(3):e1008785. doi: 10.1371/journal.pcbi.1008785. eCollection 2021 Mar. PLoS Comput Biol. 2021. PMID: 33730053 Free PMC article.
Favipiravir antiviral efficacy against SARS-CoV-2 in a hamster model.
Driouich JS, Cochin M, Lingas G, Moureau G, Touret F, Petit PR, Piorkowski G, Barthélémy K, Laprie C, Coutard B, Guedj J, de Lamballerie X, Solas C, Nougairède A. Driouich JS, et al. Among authors: solas c. Nat Commun. 2021 Mar 19;12(1):1735. doi: 10.1038/s41467-021-21992-w. Nat Commun. 2021. PMID: 33741945 Free PMC article.
146 results