Qian H - Search Results

1

A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TPN171H, a Novel Phosphodiesterase Type 5 Inhibitor, in Healthy Subjects.

Qian H, Chen Q, Liang L, Zou Y, Pu H, Xin L, Song R, Li T, Zhu H, Wang Y, Tian G, Shen J, Jiang H, Yu C, Wang Z, Jia J. Qian H, et al. Drug Des Devel Ther. 2021 Jul 6;15:2947-2959. doi: 10.2147/DDDT.S308610. eCollection 2021. Drug Des Devel Ther. 2021. PMID: 34262260 Free PMC article. Clinical Trial.

2

Multiple Dose Pharmacokinetics and Safety of Sulcardine Sulfate in Healthy Chinese Male Subjects: An Open-Label Phase I Clinical Study.

Wang W, Qian HJ, Xin L, Zhang MQ, Lu DY, Jin JM, Liu GY, Jia JY, Zheng HC, Yu C, Wang YP, Zhu F, Liu Y. Wang W, et al. Eur J Drug Metab Pharmacokinet. 2017 Aug;42(4):593-599. doi: 10.1007/s13318-016-0370-1. Eur J Drug Metab Pharmacokinet. 2017. PMID: 27550655 Clinical Trial.

3

Pharmacokinetics, safety, and tolerability of sulcardine sulfate: an open-label, single-dose, randomized study in healthy Chinese subjects.

Chen Q, Qian HJ, Wang W, Zhang MQ, Lu DY, Lu C, Jin JM, Hu CY, Liu GY, Jia JY, Zheng HC, Li XN, Yu C, Wang YP, Liu Y. Chen Q, et al. Fundam Clin Pharmacol. 2017 Feb;31(1):120-125. doi: 10.1111/fcp.12242. Epub 2016 Oct 5. Fundam Clin Pharmacol. 2017. PMID: 27599871 Clinical Trial.

4

Effects of a High-fat Meal on the Pharmacokinetics of the VEGFR Inhibitor Fruquintinib: A Randomized Phase I Study in Healthy Subjects.

Qian H, Fan S, Li K, Sai Y, Su W, Chen Q, Liu Y, Li T, Wang W, Jia J, Yu C, Liu Y. Qian H, et al. Clin Ther. 2019 Aug;41(8):1537-1544. doi: 10.1016/j.clinthera.2019.05.014. Epub 2019 Jul 1. Clin Ther. 2019. PMID: 31272709 Clinical Trial.

5

Effects of Food on the Pharmacokinetic Properties of Surufatinib: A Phase I, Single-dose, Randomized, Open-label Crossover Study in Healthy Subjects.

Qian H, Wu X, Chen Q, Li T, Wang W, Jia J, Yu C, Li K, Sai Y, Su W, Liu Y. Qian H, et al. Clin Ther. 2020 Sep;42(9):1778-1786. doi: 10.1016/j.clinthera.2020.07.010. Epub 2020 Aug 13. Clin Ther. 2020. PMID: 32800383 Clinical Trial.

6

Liquid chromatography-tandem mass spectrometric assay for TPN171 in human plasma.

Zhang M, Liu H, He J, Gui Y, Qian H, Jia J, Yu C, Wang Z, Shen JS, Liu G. Zhang M, et al. Among authors: qian h. J Pharm Biomed Anal. 2020 Nov 30;191:113634. doi: 10.1016/j.jpba.2020.113634. Epub 2020 Sep 17. J Pharm Biomed Anal. 2020. PMID: 32987249

7

A phase 1 randomized study compare the pharmacokinetics, safety and immunogenicity of HLX04 to reference bevacizumab sourced from the United States, the European Union, and China in healthy Chinese male volunteers.

Zhu X, Qian H, Sun J, Wu M, Yu C, Ding Y, Zhang X, Chai K, Li X. Zhu X, et al. Among authors: qian h. Cancer Chemother Pharmacol. 2021 Sep;88(3):465-474. doi: 10.1007/s00280-021-04297-z. Epub 2021 Jun 4. Cancer Chemother Pharmacol. 2021. PMID: 34086067 Free PMC article. Clinical Trial.

8

Safety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy subjects.

Qian HJ, Wang Y, Zhang MQ, Xie YC, Wu QQ, Liang LY, Cao Y, Duan HQ, Tian GH, Ma J, Zhang ZB, Li N, Jia JY, Zhang J, Aisa HA, Shen JS, Yu C, Jiang HL, Zhang WH, Wang Z, Liu GY. Qian HJ, et al. Acta Pharmacol Sin. 2022 Dec;43(12):3130-3138. doi: 10.1038/s41401-022-00895-6. Epub 2022 Mar 16. Acta Pharmacol Sin. 2022. PMID: 35296780 Free PMC article.

9

Safety, tolerability, and pharmacokinetics of fluoropezil (DC20), a novel acetylcholinesterase inhibitor: A phase I study in healthy young and elderly Chinese subjects.

Qian H, Yu C, Zhu H, Ding Q, Cai Y, Jing J, Xu X, Guo R, Zhang H, Liu H, Chen X, Liu Y. Qian H, et al. Clin Transl Sci. 2023 May;16(5):810-822. doi: 10.1111/cts.13490. Epub 2023 Feb 26. Clin Transl Sci. 2023. PMID: 36798012 Free PMC article. Clinical Trial.

10

A phase I study comparing the pharmacokinetics and safety of HS628 (tocilizumab biosimilar) and reference tocilizumab in healthy male subjects.

Qian H, Cheng J, Gui Y, Wang W, Liang L, Zhu H, Wu Q, Ou M, Chen Q, Yu C, Jia J. Qian H, et al. Clin Transl Sci. 2023 Sep;16(9):1704-1712. doi: 10.1111/cts.13584. Epub 2023 Jul 18. Clin Transl Sci. 2023. PMID: 37403258 Free PMC article. Clinical Trial.

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