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Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer.
Chrysostomou S, Roy R, Prischi F, Thamlikitkul L, Chapman KL, Mufti U, Peach R, Ding L, Hancock D, Moore C, Molina-Arcas M, Mauri F, Pinato DJ, Abrahams JM, Ottaviani S, Castellano L, Giamas G, Pascoe J, Moonamale D, Pirrie S, Gaunt C, Billingham L, Steven NM, Cullen M, Hrouda D, Winkler M, Post J, Cohen P, Salpeter SJ, Bar V, Zundelevich A, Golan S, Leibovici D, Lara R, Klug DR, Yaliraki SN, Barahona M, Wang Y, Downward J, Skehel JM, Ali MMU, Seckl MJ, Pardo OE. Chrysostomou S, et al. Among authors: klug dr. Sci Transl Med. 2021 Jul 14;13(602):eaba4627. doi: 10.1126/scitranslmed.aba4627. Sci Transl Med. 2021. PMID: 34261798 Free PMC article.
Detection of Drug Binding to a Target Protein Using EVV 2DIR Spectroscopy.
Sowley H, Liu Z, Davies J, Peach R, Guo R, Sim S, Long F, Holdgate G, Willison K, Zhuang W, Klug DR. Sowley H, et al. Among authors: klug dr. J Phys Chem B. 2019 May 2;123(17):3598-3606. doi: 10.1021/acs.jpcb.9b00501. Epub 2019 Mar 22. J Phys Chem B. 2019. PMID: 30848913 Free article.
Detection of complex formation and determination of intermolecular geometry through electrical anharmonic coupling of molecular vibrations using electron-vibration-vibration two-dimensional infrared spectroscopy.
Guo R, Fournier F, Donaldson PM, Gardner EM, Gould IR, Klug DR. Guo R, et al. Among authors: klug dr. Phys Chem Chem Phys. 2009 Oct 14;11(38):8417-21. doi: 10.1039/b910804a. Epub 2009 Jul 22. Phys Chem Chem Phys. 2009. PMID: 19774270 Free article.
65 results