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Generation of T-cell-redirecting bispecific antibodies with differentiated profiles of cytokine release and biodistribution by CD3 affinity tuning.
Haber L, Olson K, Kelly MP, Crawford A, DiLillo DJ, Tavaré R, Ullman E, Mao S, Canova L, Sineshchekova O, Finney J, Pawashe A, Patel S, McKay R, Rizvi S, Damko E, Chiu D, Vazzana K, Ram P, Mohrs K, D'Orvilliers A, Xiao J, Makonnen S, Hickey C, Arnold C, Giurleo J, Chen YP, Thwaites C, Dudgeon D, Bray K, Rafique A, Huang T, Delfino F, Hermann A, Kirshner JR, Retter MW, Babb R, MacDonald D, Chen G, Olson WC, Thurston G, Davis S, Lin JC, Smith E. Haber L, et al. Among authors: olson k, olson wc. Sci Rep. 2021 Jul 13;11(1):14397. doi: 10.1038/s41598-021-93842-0. Sci Rep. 2021. PMID: 34257348 Free PMC article.
A novel, native-format bispecific antibody triggering T-cell killing of B-cells is robustly active in mouse tumor models and cynomolgus monkeys.
Smith EJ, Olson K, Haber LJ, Varghese B, Duramad P, Tustian AD, Oyejide A, Kirshner JR, Canova L, Menon J, Principio J, MacDonald D, Kantrowitz J, Papadopoulos N, Stahl N, Yancopoulos GD, Thurston G, Davis S. Smith EJ, et al. Among authors: olson k. Sci Rep. 2015 Dec 11;5:17943. doi: 10.1038/srep17943. Sci Rep. 2015. PMID: 26659273 Free PMC article.
A BCMAxCD3 bispecific T cell-engaging antibody demonstrates robust antitumor efficacy similar to that of anti-BCMA CAR T cells.
DiLillo DJ, Olson K, Mohrs K, Meagher TC, Bray K, Sineshchekova O, Startz T, Kuhnert J, Retter MW, Godin S, Sharma P, Delfino F, Lin J, Smith E, Thurston G, Kirshner JR. DiLillo DJ, et al. Among authors: olson k. Blood Adv. 2021 Mar 9;5(5):1291-1304. doi: 10.1182/bloodadvances.2020002736. Blood Adv. 2021. PMID: 33651100 Free PMC article.
Ongoing Dll4-Notch signaling is required for T-cell homeostasis in the adult thymus.
Billiard F, Kirshner JR, Tait M, Danave A, Taheri S, Zhang W, Waite JC, Olson K, Chen G, Coetzee S, Hylton D, Murphy AJ, Yancopoulos GD, Thurston G, Skokos D. Billiard F, et al. Among authors: olson k. Eur J Immunol. 2011 Aug;41(8):2207-16. doi: 10.1002/eji.201041343. Epub 2011 Jul 4. Eur J Immunol. 2011. PMID: 21598246 Free article.
The relationship between body composition and left ventricular performance in women with breast, lymphoma, or sarcoma cancer.
Mabudian L, Reding K, D'Agostino RB Jr, Heiston EM, Bellissimo MP, Olson K, Ntim WO, Klepin HD, Dressler EV, Moore T, Jordan JH, O'Connell NS, Ladd A, Weaver KE, Ky B, Wagner LI, Hackney MH, Lesser GJ, Hundley WG; UPBEAT Study Team. Mabudian L, et al. Among authors: olson k. Cardiooncology. 2024 Jun 6;10(1):34. doi: 10.1186/s40959-024-00233-1. Cardiooncology. 2024. PMID: 38845066
Effect of wheat middling incorporation into wet corn distillers grains with solubles on apparent diet digestibility and ruminal fermentation characteristics in growing and finishing diets.
Duncan ZM, DeBord ZL, Pflughoeft MG, Hollenbeck WR, Titgemeyer EC, Olson KC, Blasi DA. Duncan ZM, et al. Among authors: olson kc. Transl Anim Sci. 2024 May 14;8:txae083. doi: 10.1093/tas/txae083. eCollection 2024. Transl Anim Sci. 2024. PMID: 38800104 Free PMC article.
Reaction Mechanisms of H2S Oxidation by Naphthoquinones.
Olson KR, Clear KJ, Takata T, Gao Y, Ma Z, Pfaff E, Travlos A, Luu J, Wilson K, Joseph Z, Kyle I, Kasko SM, Jones P Jr, Fukuto J, Xian M, Wu G, Straub KD. Olson KR, et al. Antioxidants (Basel). 2024 May 20;13(5):619. doi: 10.3390/antiox13050619. Antioxidants (Basel). 2024. PMID: 38790724 Free PMC article.
1,695 results