Ludwig FA - Search Results

1

In vitro and in vivo evaluation of fluorinated indanone derivatives as potential positron emission tomography agents for the imaging of monoamine oxidase B in the brain.

Dukić-Stefanović S, Hang Lai T, Toussaint M, Clauß O, Jevtić II, Penjišević JZ, Andrić D, Ludwig FA, Gündel D, Deuther-Conrad W, Kostić-Rajačić SV, Brust P, Teodoro R. Dukić-Stefanović S, et al. Among authors: ludwig fa. Bioorg Med Chem Lett. 2021 Sep 15;48:128254. doi: 10.1016/j.bmcl.2021.128254. Epub 2021 Jul 10. Bioorg Med Chem Lett. 2021. PMID: 34256118

2

Radiofluorination and biological evaluation of N-aryl-oxadiazolyl-propionamides as potential radioligands for PET imaging of cannabinoid CB2 receptors.

Teodoro R, Moldovan RP, Lueg C, Günther R, Donat CK, Ludwig FA, Fischer S, Deuther-Conrad W, Wünsch B, Brust P. Teodoro R, et al. Among authors: ludwig fa. Org Med Chem Lett. 2013 Sep 24;3(1):11. doi: 10.1186/2191-2858-3-11. Org Med Chem Lett. 2013. PMID: 24063584 Free PMC article.

3

Asymmetric Synthesis of Spirocyclic 2-Benzopyrans for Positron Emission Tomography of σ1 Receptors in the Brain.

Holl K, Schepmann D, Fischer S, Ludwig FA, Hiller A, Donat CK, Deuther-Conrad W, Brust P, Wünsch B. Holl K, et al. Among authors: ludwig fa. Pharmaceuticals (Basel). 2014 Jan 22;7(1):78-112. doi: 10.3390/ph7010078. Pharmaceuticals (Basel). 2014. PMID: 24451404 Free PMC article.

4

Development of a Novel Nonpeptidic (18)F-Labeled Radiotracer for in Vivo Imaging of Oxytocin Receptors with Positron Emission Tomography.

Wenzel B, Mollitor J, Deuther-Conrad W, Dukic-Stefanovic S, Kranz M, Vraka C, Teodoro R, Günther R, Donat CK, Ludwig FA, Fischer S, Smits R, Wadsak W, Mitterhauser M, Steinbach J, Hoepping A, Brust P. Wenzel B, et al. Among authors: ludwig fa. J Med Chem. 2016 Mar 10;59(5):1800-17. doi: 10.1021/acs.jmedchem.5b01080. Epub 2016 Feb 3. J Med Chem. 2016. PMID: 26796795

5

Development of a New Radiofluorinated Quinoline Analog for PET Imaging of Phosphodiesterase 5 (PDE5) in Brain.

Liu J, Wenzel B, Dukic-Stefanovic S, Teodoro R, Ludwig FA, Deuther-Conrad W, Schröder S, Chezal JM, Moreau E, Brust P, Maisonial-Besset A. Liu J, et al. Among authors: ludwig fa. Pharmaceuticals (Basel). 2016 Apr 21;9(2):22. doi: 10.3390/ph9020022. Pharmaceuticals (Basel). 2016. PMID: 27110797 Free PMC article.

6

LC-MS Supported Studies on the in Vitro Metabolism of both Enantiomers of Flubatine and the in Vivo Metabolism of (+)-[(18)F]Flubatine-A Positron Emission Tomography Radioligand for Imaging α4β2 Nicotinic Acetylcholine Receptors.

Ludwig FA, Smits R, Fischer S, Donat CK, Hoepping A, Brust P, Steinbach J. Ludwig FA, et al. Molecules. 2016 Sep 8;21(9):1200. doi: 10.3390/molecules21091200. Molecules. 2016. PMID: 27617996 Free PMC article.

7

Comparison of in Silico, Electrochemical, in Vitro and in Vivo Metabolism of a Homologous Series of (Radio)fluorinated σ₁ Receptor Ligands Designed for Positron Emission Tomography.

Wiese C, Große Maestrup E, Galla F, Schepmann D, Hiller A, Fischer S, Ludwig FA, Deuther-Conrad W, Donat CK, Brust P, Büter L, Karst U, Wünsch B. Wiese C, et al. Among authors: ludwig fa. ChemMedChem. 2016 Nov 7;11(21):2445-2458. doi: 10.1002/cmdc.201600366. Epub 2016 Sep 28. ChemMedChem. 2016. PMID: 27677767

8

Radiosynthesis of (S)-[¹⁸F]T1: The first PET radioligand for molecular imaging of α3β4 nicotinic acetylcholine receptors.

Sarasamkan J, Fischer S, Deuther-Conrad W, Ludwig FA, Scheunemann M, Arunrungvichian K, Vajragupta O, Brust P. Sarasamkan J, et al. Among authors: ludwig fa. Appl Radiat Isot. 2017 Jun;124:106-113. doi: 10.1016/j.apradiso.2017.03.015. Epub 2017 Mar 18. Appl Radiat Isot. 2017. PMID: 28365525

9

Exploring the Metabolism of (+)-[¹⁸F]Flubatine in Vitro and in Vivo: LC-MS/MS Aided Identification of Radiometabolites in a Clinical PET Study.

Ludwig FA, Fischer S, Smits R, Deuther-Conrad W, Hoepping A, Tiepolt S, Patt M, Sabri O, Brust P. Ludwig FA, et al. Molecules. 2018 Feb 20;23(2):464. doi: 10.3390/molecules23020464. Molecules. 2018. PMID: 29461507 Free PMC article.

10

N^ε-Acryloyllysine Piperazides as Irreversible Inhibitors of Transglutaminase 2: Synthesis, Structure-Activity Relationships, and Pharmacokinetic Profiling.

Wodtke R, Hauser C, Ruiz-Gómez G, Jäckel E, Bauer D, Lohse M, Wong A, Pufe J, Ludwig FA, Fischer S, Hauser S, Greif D, Pisabarro MT, Pietzsch J, Pietsch M, Löser R. Wodtke R, et al. Among authors: ludwig fa. J Med Chem. 2018 May 24;61(10):4528-4560. doi: 10.1021/acs.jmedchem.8b00286. Epub 2018 May 10. J Med Chem. 2018. PMID: 29664627

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