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Discovery of EST73502, a Dual μ-Opioid Receptor Agonist and σ1 Receptor Antagonist Clinical Candidate for the Treatment of Pain.
García M, Virgili M, Alonso M, Alegret C, Farran J, Fernández B, Bordas M, Pascual R, Burgueño J, Vidal-Torres A, Fernández de Henestrosa AR, Ayet E, Merlos M, Vela JM, Plata-Salamán CR, Almansa C. García M, et al. J Med Chem. 2020 Dec 24;63(24):15508-15526. doi: 10.1021/acs.jmedchem.0c01127. Epub 2020 Oct 16. J Med Chem. 2020. PMID: 33064947
EST64454: a Highly Soluble σ1 Receptor Antagonist Clinical Candidate for Pain Management.
Díaz JL, García M, Torrens A, Caamaño AM, Enjo J, Sicre C, Lorente A, Port A, Montero A, Yeste S, Álvarez I, Martín M, Maldonado R, de la Puente B, Vidal-Torres A, Cendán CM, Vela JM, Almansa C. Díaz JL, et al. Among authors: garcia m. J Med Chem. 2020 Dec 10;63(23):14979-14988. doi: 10.1021/acs.jmedchem.0c01575. Epub 2020 Nov 25. J Med Chem. 2020. PMID: 33237785
Piperazinyl Bicyclic Derivatives as Selective Ligands of the α2δ-1 Subunit of Voltage-Gated Calcium Channels.
Fernández A, Díaz JL, García M, Rodríguez-Escrich S, Lorente A, Enrech R, Dordal A, Portillo-Salido E, Porras M, Fernández B, Reinoso RF, Vela JM, Almansa C. Fernández A, et al. Among authors: garcia m. ACS Med Chem Lett. 2021 Oct 5;12(11):1802-1809. doi: 10.1021/acsmedchemlett.1c00416. eCollection 2021 Nov 11. ACS Med Chem Lett. 2021. PMID: 34795870 Free PMC article.
Bispecific sigma-1 receptor antagonism and mu-opioid receptor partial agonism: WLB-73502, an analgesic with improved efficacy and safety profile compared to strong opioids.
Vidal-Torres A, Fernández-Pastor B, García M, Ayet E, Cabot A, Burgueño J, Monroy X, Aubel B, Codony X, Romero L, Pascual R, Serafini MT, Encina G, Almansa C, Zamanillo D, Merlos M, Vela JM. Vidal-Torres A, et al. Among authors: garcia m. Acta Pharm Sin B. 2023 Jan;13(1):82-99. doi: 10.1016/j.apsb.2022.09.018. Epub 2022 Sep 25. Acta Pharm Sin B. 2023. PMID: 36815042 Free PMC article.
The Role of Stigma and Resilience in Healthcare Engagement Among Transgender Latinas in the U.S. South: Baseline Findings from the ChiCAS Study.
Goldenberg T, Tanner AE, McGuire T, Alonzo J, Mann-Jackson L, Refugio Aviles L, Galindo CA, Bessler PA, Courtenay-Quirk C, Garcia M, Reboussin BA, Rhodes SD. Goldenberg T, et al. Among authors: garcia m. J Immigr Minor Health. 2024 May 29. doi: 10.1007/s10903-024-01605-6. Online ahead of print. J Immigr Minor Health. 2024. PMID: 38809298
Exploring the FAO Minimum Dietary Diversity Indicator as a Suitable Proxy of Micronutrient Adequacy in Men and Women Across Reproductive and Non-reproductive Ages in 8 Latin American Countries.
Gómez G, Monge-Rojas R, Vargas-Quesada R, Previdelli AN, Quesada D, Kovalskys I, Herrera-Cuenca M, Cortes LY, García MCY, Liria-Domínguez R, Rigotti A, Fisberg RM, Ferrari G, Fisberg M, Brenes JC. Gómez G, et al. Among authors: garcia mcy. Food Nutr Bull. 2024 May 28:3795721241242920. doi: 10.1177/03795721241242920. Online ahead of print. Food Nutr Bull. 2024. PMID: 38807356
Buprenorphine Use for Analgesia in Palliative Care.
Jackson LK, Poon IO, Garcia MA, Imam S, Braun UK. Jackson LK, et al. Among authors: garcia ma. Pharmacy (Basel). 2024 May 13;12(3):78. doi: 10.3390/pharmacy12030078. Pharmacy (Basel). 2024. PMID: 38804470 Free PMC article.
9,779 results