Pore N - Search Results

1

Resistance to Durvalumab and Durvalumab plus Tremelimumab Is Associated with Functional STK11 Mutations in Patients with Non-Small Cell Lung Cancer and Is Reversed by STAT3 Knockdown.

Pore N, Wu S, Standifer N, Jure-Kunkel M, de Los Reyes M, Shrestha Y, Halpin R, Rothstein R, Mulgrew K, Blackmore S, Martin P, Meekin J 3rd, Griffin M, Bisha I, Proia TA, Miragaia RJ, Herbst R, Gupta A, Abdullah SE, Raja R, Frigault MM, Barrett JC, Dennis PA, Ascierto ML, Oberst MD. Pore N, et al. Cancer Discov. 2021 Nov;11(11):2828-2845. doi: 10.1158/2159-8290.CD-20-1543. Epub 2021 Jul 6. Cancer Discov. 2021. PMID: 34230008

2

Blocking ADAM17 Function with a Monoclonal Antibody Improves Sepsis Survival in a Murine Model of Polymicrobial Sepsis.

Mishra HK, Ma J, Mendez D, Hullsiek R, Pore N, Walcheck B. Mishra HK, et al. Among authors: pore n. Int J Mol Sci. 2020 Sep 12;21(18):6688. doi: 10.3390/ijms21186688. Int J Mol Sci. 2020. PMID: 32932701 Free PMC article.

3

Activation of ADAM17 by IL-15 Limits Human NK Cell Proliferation.

Mishra HK, Dixon KJ, Pore N, Felices M, Miller JS, Walcheck B. Mishra HK, et al. Among authors: pore n. Front Immunol. 2021 Jul 22;12:711621. doi: 10.3389/fimmu.2021.711621. eCollection 2021. Front Immunol. 2021. PMID: 34367174 Free PMC article.

4

Anti-ADAM17 monoclonal antibody MEDI3622 increases IFNγ production by human NK cells in the presence of antibody-bound tumor cells.

Mishra HK, Pore N, Michelotti EF, Walcheck B. Mishra HK, et al. Among authors: pore n. Cancer Immunol Immunother. 2018 Sep;67(9):1407-1416. doi: 10.1007/s00262-018-2193-1. Epub 2018 Jul 5. Cancer Immunol Immunother. 2018. PMID: 29978334 Free PMC article.

5

In Vivo Loss of Function Screening Reveals Carbonic Anhydrase IX as a Key Modulator of Tumor Initiating Potential in Primary Pancreatic Tumors.

Pore N, Jalla S, Liu Z, Higgs B, Sorio C, Scarpa A, Hollingsworth R, Tice DA, Michelotti E. Pore N, et al. Neoplasia. 2015 Jun;17(6):473-80. doi: 10.1016/j.neo.2015.05.001. Neoplasia. 2015. PMID: 26152355 Free PMC article.

6

Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir.

Jiang Z, Pore N, Cerniglia GJ, Mick R, Georgescu MM, Bernhard EJ, Hahn SM, Gupta AK, Maity A. Jiang Z, et al. Among authors: pore n. Cancer Res. 2007 May 1;67(9):4467-73. doi: 10.1158/0008-5472.CAN-06-3398. Cancer Res. 2007. PMID: 17483362

7

EGFR tyrosine kinase inhibitors decrease VEGF expression by both hypoxia-inducible factor (HIF)-1-independent and HIF-1-dependent mechanisms.

Pore N, Jiang Z, Gupta A, Cerniglia G, Kao GD, Maity A. Pore N, et al. Cancer Res. 2006 Mar 15;66(6):3197-204. doi: 10.1158/0008-5472.CAN-05-3090. Cancer Res. 2006. PMID: 16540671

8

Akt1 activation can augment hypoxia-inducible factor-1alpha expression by increasing protein translation through a mammalian target of rapamycin-independent pathway.

Pore N, Jiang Z, Shu HK, Bernhard E, Kao GD, Maity A. Pore N, et al. Mol Cancer Res. 2006 Jul;4(7):471-9. doi: 10.1158/1541-7786.MCR-05-0234. Mol Cancer Res. 2006. PMID: 16849522

9

Nelfinavir down-regulates hypoxia-inducible factor 1alpha and VEGF expression and increases tumor oxygenation: implications for radiotherapy.

Pore N, Gupta AK, Cerniglia GJ, Jiang Z, Bernhard EJ, Evans SM, Koch CJ, Hahn SM, Maity A. Pore N, et al. Cancer Res. 2006 Sep 15;66(18):9252-9. doi: 10.1158/0008-5472.CAN-06-1239. Cancer Res. 2006. PMID: 16982770

10

HIV protease inhibitors decrease VEGF/HIF-1alpha expression and angiogenesis in glioblastoma cells.

Pore N, Gupta AK, Cerniglia GJ, Maity A. Pore N, et al. Neoplasia. 2006 Nov;8(11):889-95. doi: 10.1593/neo.06535. Neoplasia. 2006. PMID: 17132220 Free PMC article.

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