Sáez-Orellana F - Search Results

1

Regulation of PPARα by APP in Alzheimer disease affects the pharmacological modulation of synaptic activity.

Sáez-Orellana F, Leroy T, Ribeiro F, Kreis A, Leroy K, Lalloyer F, Baugé E, Staels B, Duyckaerts C, Brion JP, Gailly P, Octave JN, Pierrot N. Sáez-Orellana F, et al. JCI Insight. 2021 Aug 23;6(16):e150099. doi: 10.1172/jci.insight.150099. JCI Insight. 2021. PMID: 34228639 Free PMC article.

2

Alzheimer's Disease, a Lipid Story: Involvement of Peroxisome Proliferator-Activated Receptor α.

Sáez-Orellana F, Octave JN, Pierrot N. Sáez-Orellana F, et al. Cells. 2020 May 14;9(5):1215. doi: 10.3390/cells9051215. Cells. 2020. PMID: 32422896 Free PMC article. Review.

3

P2X receptor overexpression induced by soluble oligomers of amyloid beta peptide potentiates synaptic failure and neuronal dyshomeostasis in cellular models of Alzheimer's disease.

Sáez-Orellana F, Fuentes-Fuentes MC, Godoy PA, Silva-Grecchi T, Panes JD, Guzmán L, Yévenes GE, Gavilán J, Egan TM, Aguayo LG, Fuentealba J. Sáez-Orellana F, et al. Neuropharmacology. 2018 Jan;128:366-378. doi: 10.1016/j.neuropharm.2017.10.027. Epub 2017 Oct 25. Neuropharmacology. 2018. PMID: 29079292 Free PMC article.

4

Modulation of neuronal nicotinic receptor by quinolizidine alkaloids causes neuroprotection on a cellular Alzheimer model.

Araya JA, Ramírez AE, Figueroa-Aroca D, Sotes GJ, Pérez C, Becerra J, Saez-Orellana F, Guzmán L, Aguayo LG, Fuentealba J. Araya JA, et al. J Alzheimers Dis. 2014;42(1):143-55. doi: 10.3233/JAD-132045. J Alzheimers Dis. 2014. PMID: 24825567

5

ATP leakage induces P2XR activation and contributes to acute synaptic excitotoxicity induced by soluble oligomers of β-amyloid peptide in hippocampal neurons.

Sáez-Orellana F, Godoy PA, Bastidas CY, Silva-Grecchi T, Guzmán L, Aguayo LG, Fuentealba J. Sáez-Orellana F, et al. Neuropharmacology. 2016 Jan;100:116-23. doi: 10.1016/j.neuropharm.2015.04.005. Epub 2015 Apr 17. Neuropharmacology. 2016. PMID: 25896766

6

Synaptic silencing and plasma membrane dyshomeostasis induced by amyloid-β peptide are prevented by Aristotelia chilensis enriched extract.

Fuentealba J, Dibarrart A, Saez-Orellana F, Fuentes-Fuentes MC, Oyanedel CN, Guzmán J, Perez C, Becerra J, Aguayo LG. Fuentealba J, et al. J Alzheimers Dis. 2012;31(4):879-89. doi: 10.3233/JAD-2012-120229. J Alzheimers Dis. 2012. PMID: 22728896

7

A Natural Benzofuran from the Patagonic Aleurodiscus vitellinus Fungus has Potent Neuroprotective Properties on a Cellular Model of Amyloid-β Peptide Toxicity.

González-Ramírez M, Gavilán J, Silva-Grecchi T, Cajas-Madriaga D, Triviño S, Becerra J, Saez-Orellana F, Pérez C, Fuentealba J. González-Ramírez M, et al. Among authors: saez orellana f. J Alzheimers Dis. 2018;61(4):1463-1475. doi: 10.3233/JAD-170958. J Alzheimers Dis. 2018. PMID: 29376877

8

Synaptic failure and adenosine triphosphate imbalance induced by amyloid-β aggregates are prevented by blueberry-enriched polyphenols extract.

Fuentealba J, Dibarrart AJ, Fuentes-Fuentes MC, Saez-Orellana F, Quiñones K, Guzmán L, Perez C, Becerra J, Aguayo LG. Fuentealba J, et al. J Neurosci Res. 2011 Sep;89(9):1499-508. doi: 10.1002/jnr.22679. Epub 2011 Jun 6. J Neurosci Res. 2011. PMID: 21647937

9

Neuroactive alkaloids that modulate the neuronal nicotinic receptor and provide neuroprotection in an Alzheimer's disease model: the case of Teline monspessulana.

Fuentealba J, Saez-Orellana F. Fuentealba J, et al. Among authors: saez orellana f. Neural Regen Res. 2014 Nov 1;9(21):1880-1. doi: 10.4103/1673-5374.145349. Neural Regen Res. 2014. PMID: 25558235 Free PMC article. No abstract available.

10

Microglial Activation Modulated by P2X4R in Ischemia and Repercussions in Alzheimer's Disease.

Castillo C, Saez-Orellana F, Godoy PA, Fuentealba J. Castillo C, et al. Among authors: saez orellana f. Front Physiol. 2022 Feb 23;13:814999. doi: 10.3389/fphys.2022.814999. eCollection 2022. Front Physiol. 2022. PMID: 35283778 Free PMC article. Review.

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