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The Tuberculosis Drug Accelerator at year 10: what have we learned?
Aldridge BB, Barros-Aguirre D, Barry CE 3rd, Bates RH, Berthel SJ, Boshoff HI, Chibale K, Chu XJ, Cooper CB, Dartois V, Duncan K, Fotouhi N, Gusovsky F, Hipskind PA, Kempf DJ, Lelièvre J, Lenaerts AJ, McNamara CW, Mizrahi V, Nathan C, Olsen DB, Parish T, Petrassi HM, Pym A, Rhee KY, Robertson GT, Rock JM, Rubin EJ, Russell B, Russell DG, Sacchettini JC, Schnappinger D, Schrimpf M, Upton AM, Warner P, Wyatt PG, Yuan Y. Aldridge BB, et al. Nat Med. 2021 Aug;27(8):1333-1337. doi: 10.1038/s41591-021-01442-2. Nat Med. 2021. PMID: 34226736 Free PMC article.
Accelerating Early Antituberculosis Drug Discovery by Creating Mycobacterial Indicator Strains That Predict Mode of Action.
Boot M, Commandeur S, Subudhi AK, Bahira M, Smith TC 2nd, Abdallah AM, van Gemert M, Lelièvre J, Ballell L, Aldridge BB, Pain A, Speer A, Bitter W. Boot M, et al. Among authors: aldridge bb. Antimicrob Agents Chemother. 2018 Jun 26;62(7):e00083-18. doi: 10.1128/AAC.00083-18. Print 2018 Jul. Antimicrob Agents Chemother. 2018. PMID: 29661879 Free PMC article.
Setting Our Sights on Infectious Diseases.
De Rycker M, Horn D, Aldridge B, Amewu RK, Barry CE 3rd, Buckner FS, Cook S, Ferguson MAJ, Gobeau N, Herrmann J, Herrling P, Hope W, Keiser J, Lafuente-Monasterio MJ, Leeson PD, Leroy D, Manjunatha UH, McCarthy J, Miles TJ, Mizrahi V, Moshynets O, Niles J, Overington JP, Pottage J, Rao SPS, Read KD, Ribeiro I, Silver LL, Southern J, Spangenberg T, Sundar S, Taylor C, Van Voorhis W, White NJ, Wyllie S, Wyatt PG, Gilbert IH. De Rycker M, et al. ACS Infect Dis. 2020 Jan 10;6(1):3-13. doi: 10.1021/acsinfecdis.9b00371. Epub 2019 Dec 6. ACS Infect Dis. 2020. PMID: 31808676 Free PMC article.
Pharmacokinetics and Target Attainment of SQ109 in Plasma and Human-Like Tuberculosis Lesions in Rabbits.
Egbelowo O, Sarathy JP, Gausi K, Zimmerman MD, Wang H, Wijnant GJ, Kaya F, Gengenbacher M, Van N, Degefu Y, Nacy C, Aldridge BB, Carter CL, Denti P, Dartois V. Egbelowo O, et al. Among authors: aldridge bb. Antimicrob Agents Chemother. 2021 Aug 17;65(9):e0002421. doi: 10.1128/AAC.00024-21. Epub 2021 Aug 17. Antimicrob Agents Chemother. 2021. PMID: 34228540 Free PMC article.
Tuberculosis treatment failure associated with evolution of antibiotic resilience.
Liu Q, Zhu J, Dulberger CL, Stanley S, Wilson S, Chung ES, Wang X, Culviner P, Liu YJ, Hicks ND, Babunovic GH, Giffen SR, Aldridge BB, Garner EC, Rubin EJ, Chao MC, Fortune SM. Liu Q, et al. Among authors: aldridge bb. Science. 2022 Dec 9;378(6624):1111-1118. doi: 10.1126/science.abq2787. Epub 2022 Dec 8. Science. 2022. PMID: 36480634 Free PMC article.
The Spectrum of Drug Susceptibility in Mycobacteria.
Aldridge BB, Keren I, Fortune SM. Aldridge BB, et al. Microbiol Spectr. 2014 Oct;2(5). doi: 10.1128/microbiolspec.MGM2-0031-2013. Microbiol Spectr. 2014. PMID: 26104360 Free article. Review.
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