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Mutational Landscape of the Proglucagon-Derived Peptides.
Lindquist P, Madsen JS, Bräuner-Osborne H, Rosenkilde MM, Hauser AS. Lindquist P, et al. Among authors: hauser as. Front Endocrinol (Lausanne). 2021 Jun 17;12:698511. doi: 10.3389/fendo.2021.698511. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34220721 Free PMC article.
The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW.
Nøhr AC, Shehata MA, Hauser AS, Isberg V, Mokrosinski J, Andersen KB, Farooqi IS, Pedersen DS, Gloriam DE, Bräuner-Osborne H. Nøhr AC, et al. Among authors: hauser as. Neurochem Int. 2017 Jan;102:105-113. doi: 10.1016/j.neuint.2016.11.012. Epub 2016 Dec 1. Neurochem Int. 2017. PMID: 27916541 Free PMC article.
Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors.
Foster SR, Hauser AS, Vedel L, Strachan RT, Huang XP, Gavin AC, Shah SD, Nayak AP, Haugaard-Kedström LM, Penn RB, Roth BL, Bräuner-Osborne H, Gloriam DE. Foster SR, et al. Among authors: hauser as. Cell. 2019 Oct 31;179(4):895-908.e21. doi: 10.1016/j.cell.2019.10.010. Cell. 2019. PMID: 31675498 Free PMC article.
Ligand-directed bias of G protein signaling at the dopamine D2 receptor.
Von Moo E, Harpsøe K, Hauser AS, Masuho I, Bräuner-Osborne H, Gloriam DE, Martemyanov KA. Von Moo E, et al. Among authors: hauser as. Cell Chem Biol. 2022 Feb 17;29(2):226-238.e4. doi: 10.1016/j.chembiol.2021.07.004. Epub 2021 Jul 23. Cell Chem Biol. 2022. PMID: 34302750 Free PMC article.
Loss of Function Glucose-Dependent Insulinotropic Polypeptide Receptor Variants Are Associated With Alterations in BMI, Bone Strength and Cardiovascular Outcomes.
Kizilkaya HS, Sørensen KV, Kibsgaard CJ, Gasbjerg LS, Hauser AS, Sparre-Ulrich AH, Grarup N, Rosenkilde MM. Kizilkaya HS, et al. Among authors: hauser as. Front Cell Dev Biol. 2021 Oct 25;9:749607. doi: 10.3389/fcell.2021.749607. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34760890 Free PMC article.
Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes.
Melchiorsen JU, Sørensen KV, Bork-Jensen J, Kizilkaya HS, Gasbjerg LS, Hauser AS, Rungby J, Sørensen HT, Vaag A, Nielsen JS, Pedersen O, Linneberg A, Hartmann B, Gjesing AP, Holst JJ, Hansen T, Rosenkilde MM, Grarup N. Melchiorsen JU, et al. Among authors: hauser as. J Clin Endocrinol Metab. 2023 Oct 18;108(11):2821-2833. doi: 10.1210/clinem/dgad290. J Clin Endocrinol Metab. 2023. PMID: 37235780 Free PMC article.
35 results