Bräuner-Osborne H - Search Results

1

Mutational Landscape of the Proglucagon-Derived Peptides.

Lindquist P, Madsen JS, Bräuner-Osborne H, Rosenkilde MM, Hauser AS. Lindquist P, et al. Front Endocrinol (Lausanne). 2021 Jun 17;12:698511. doi: 10.3389/fendo.2021.698511. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34220721 Free PMC article.

2

Agonists and inverse agonists for the herpesvirus 8-encoded constitutively active seven-transmembrane oncogene product, ORF-74.

Rosenkilde MM, Kledal TN, Bräuner-Osborne H, Schwartz TW. Rosenkilde MM, et al. J Biol Chem. 1999 Jan 8;274(2):956-61. doi: 10.1074/jbc.274.2.956. J Biol Chem. 1999. PMID: 9873037 Free article.

3

Increased susceptibility to diet-induced obesity in GPRC6A receptor knockout mice.

Clemmensen C, Smajilovic S, Madsen AN, Klein AB, Holst B, Bräuner-Osborne H. Clemmensen C, et al. J Endocrinol. 2013 Apr 15;217(2):151-60. doi: 10.1530/JOE-12-0550. Print 2013 May. J Endocrinol. 2013. PMID: 23428581

4

The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW.

Nøhr AC, Shehata MA, Hauser AS, Isberg V, Mokrosinski J, Andersen KB, Farooqi IS, Pedersen DS, Gloriam DE, Bräuner-Osborne H. Nøhr AC, et al. Neurochem Int. 2017 Jan;102:105-113. doi: 10.1016/j.neuint.2016.11.012. Epub 2016 Dec 1. Neurochem Int. 2017. PMID: 27916541 Free PMC article.

5

Identification of Histamine H₃ Receptor Ligands Using a New Crystal Structure Fragment-based Method.

Frandsen IO, Boesgaard MW, Fidom K, Hauser AS, Isberg V, Bräuner-Osborne H, Wellendorph P, Gloriam DE. Frandsen IO, et al. Sci Rep. 2017 Jul 6;7(1):4829. doi: 10.1038/s41598-017-05058-w. Sci Rep. 2017. PMID: 28684785 Free PMC article.

6

Human GIP(3-30)NH₂ inhibits G protein-dependent as well as G protein-independent signaling and is selective for the GIP receptor with high-affinity binding to primate but not rodent GIP receptors.

Gabe MBN, Sparre-Ulrich AH, Pedersen MF, Gasbjerg LS, Inoue A, Bräuner-Osborne H, Hartmann B, Rosenkilde MM. Gabe MBN, et al. Biochem Pharmacol. 2018 Apr;150:97-107. doi: 10.1016/j.bcp.2018.01.040. Epub 2018 Feb 3. Biochem Pharmacol. 2018. PMID: 29378179

7

Enhanced agonist residence time, internalization rate and signalling of the GIP receptor variant [E354Q] facilitate receptor desensitization and long-term impairment of the GIP system.

Gabe MBN, van der Velden WJC, Gadgaard S, Smit FX, Hartmann B, Bräuner-Osborne H, Rosenkilde MM. Gabe MBN, et al. Basic Clin Pharmacol Toxicol. 2020 Jun;126 Suppl 6(Suppl 6):122-132. doi: 10.1111/bcpt.13289. Epub 2019 Aug 19. Basic Clin Pharmacol Toxicol. 2020. PMID: 31299132 Free PMC article.

8

G protein-coupled receptor pharmacology-The next generation.

Bräuner-Osborne H, Rosenkilde MM, Gether U, Gloriam DE. Bräuner-Osborne H, et al. Basic Clin Pharmacol Toxicol. 2020 Jun;126 Suppl 6:3-4. doi: 10.1111/bcpt.13291. Epub 2019 Aug 21. Basic Clin Pharmacol Toxicol. 2020. PMID: 31301209 Free article. No abstract available.

9

Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors.

Foster SR, Hauser AS, Vedel L, Strachan RT, Huang XP, Gavin AC, Shah SD, Nayak AP, Haugaard-Kedström LM, Penn RB, Roth BL, Bräuner-Osborne H, Gloriam DE. Foster SR, et al. Cell. 2019 Oct 31;179(4):895-908.e21. doi: 10.1016/j.cell.2019.10.010. Cell. 2019. PMID: 31675498 Free PMC article.

10

Novel approaches leading towards peptide GPCR de-orphanisation.

Hauser AS, Gloriam DE, Bräuner-Osborne H, Foster SR. Hauser AS, et al. Br J Pharmacol. 2020 Mar;177(5):961-968. doi: 10.1111/bph.14950. Epub 2020 Feb 3. Br J Pharmacol. 2020. PMID: 31863461 Free PMC article. Review.

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