Kohout T - Search Results

1

Pharmacological, Pharmacokinetic, Pharmacodynamic and Physicochemical Characterization of FE 205030: A Potent, Fast Acting, Injectable CGRP Receptor Antagonist for the Treatment of Acute Episodic Migraine.

Srinivasan K, Kozminski K, Zhang Y, Wisniewski K, Kohout T, Wisniewska H, Harris G, Lindstrom B, Hargrove D. Srinivasan K, et al. Among authors: kohout t. J Pharm Sci. 2022 Jan;111(1):247-261. doi: 10.1016/j.xphs.2021.06.034. Epub 2021 Jul 2. J Pharm Sci. 2022. PMID: 34217775

2

Additive effect of simultaneous continuous administration of degarelix and TAK-448 on LH suppression in a castrated rat model.

Stalewski J, Hargrove DM, Wolfe M, Kohout TA, Kamal A. Stalewski J, et al. Among authors: kohout ta. Eur J Pharmacol. 2018 Apr 5;824:24-29. doi: 10.1016/j.ejphar.2018.01.033. Epub 2018 Feb 3. Eur J Pharmacol. 2018. PMID: 29378196

3

Pharmacological characterization of a novel nonpeptide antagonist of the human gonadotropin-releasing hormone receptor, NBI-42902.

Struthers RS, Xie Q, Sullivan SK, Reinhart GJ, Kohout TA, Zhu YF, Chen C, Liu XJ, Ling N, Yang W, Maki RA, Bonneville AK, Chen TK, Bozigian HP. Struthers RS, et al. Endocrinology. 2007 Feb;148(2):857-67. doi: 10.1210/en.2006-1213. Epub 2006 Nov 9. Endocrinology. 2007. PMID: 17095587

4

Trapping of a nonpeptide ligand by the extracellular domains of the gonadotropin-releasing hormone receptor results in insurmountable antagonism.

Kohout TA, Xie Q, Reijmers S, Finn KJ, Guo Z, Zhu YF, Struthers RS. Kohout TA, et al. Mol Pharmacol. 2007 Aug;72(2):238-47. doi: 10.1124/mol.107.035535. Epub 2007 Apr 4. Mol Pharmacol. 2007. PMID: 17409285

5

Kisspeptin treatment induces gonadotropic responses and rescues ovulation in a subset of preclinical models and women with polycystic ovary syndrome.

Romero-Ruiz A, Skorupskaite K, Gaytan F, Torres E, Perdices-Lopez C, Mannaerts BM, Qi S, Leon S, Manfredi-Lozano M, Lopez-Rodriguez C, Avendaño MS, Sanchez-Garrido MA, Vazquez MJ, Pinilla L, van Duin M, Kohout TA, Anderson RA, Tena-Sempere M. Romero-Ruiz A, et al. Among authors: kohout ta. Hum Reprod. 2019 Dec 1;34(12):2495-2512. doi: 10.1093/humrep/dez205. Hum Reprod. 2019. PMID: 31820802 Free PMC article. Clinical Trial.

6

Distinct conformations of the corticotropin releasing factor type 1 receptor adopted following agonist and antagonist binding are differentially regulated.

Perry SJ, Junger S, Kohout TA, Hoare SR, Struthers RS, Grigoriadis DE, Maki RA. Perry SJ, et al. J Biol Chem. 2005 Mar 25;280(12):11560-8. doi: 10.1074/jbc.M412914200. Epub 2005 Jan 14. J Biol Chem. 2005. PMID: 15653688 Free article.

7

Differential desensitization, receptor phosphorylation, beta-arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7.

Kohout TA, Nicholas SL, Perry SJ, Reinhart G, Junger S, Struthers RS. Kohout TA, et al. J Biol Chem. 2004 May 28;279(22):23214-22. doi: 10.1074/jbc.M402125200. Epub 2004 Mar 30. J Biol Chem. 2004. PMID: 15054093 Free article.

8

Adrenomedullin improves fertility and promotes pinopodes and cell junctions in the peri-implantation endometrium.

Matson BC, Pierce SL, Espenschied ST, Holle E, Sweatt IH, Davis ES, Tarran R, Young SL, Kohout TA, van Duin M, Caron KM. Matson BC, et al. Among authors: kohout ta. Biol Reprod. 2017 Sep 1;97(3):466-477. doi: 10.1093/biolre/iox101. Biol Reprod. 2017. PMID: 29025060 Free PMC article.

9

Cabergoline Stimulates Human Endometrial Stromal Cell Decidualization and Reverses Effects of Interleukin-1β In Vitro.

Yu J, Berga SL, Meng Q, Xia M, Kohout TA, van Duin M, Taylor RN. Yu J, et al. Among authors: kohout ta. J Clin Endocrinol Metab. 2021 Nov 19;106(12):3591-3604. doi: 10.1210/clinem/dgab511. J Clin Endocrinol Metab. 2021. PMID: 34260712 Free PMC article.

10

beta-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking.

Kohout TA, Lin FS, Perry SJ, Conner DA, Lefkowitz RJ. Kohout TA, et al. Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1601-6. doi: 10.1073/pnas.98.4.1601. Epub 2001 Feb 6. Proc Natl Acad Sci U S A. 2001. PMID: 11171997 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

42 results

Search Page