Nussinov R - Search Results

1

Novel MAPK/AKT-impairing germline NRAS variant identified in a melanoma-prone family.

Brown KM, Xu M, Sargen M, Jang H, Zhang M, Zhang T, Zhu B, Jones K, Kim J, Mendoza L, Hayward NK, Tucker MA, Goldstein AM, Yang XR, Stewart DR, Hicks B, Consonni D, Pesatori AC, Fargnoli MC, Peris K, Stratigos A, Menin C, Ghiorzo P, Puig S, Nagore E; MelaNostrum Consortium; Andresson T, Nussinov R, Calista D, Landi MT. Brown KM, et al. Among authors: nussinov r. Fam Cancer. 2022 Jul;21(3):347-355. doi: 10.1007/s10689-021-00267-9. Epub 2021 Jul 3. Fam Cancer. 2022. PMID: 34215961 Free PMC article.

2

Conformational study of the protegrin-1 (PG-1) dimer interaction with lipid bilayers and its effect.

Jang H, Ma B, Nussinov R. Jang H, et al. Among authors: nussinov r. BMC Struct Biol. 2007 Apr 2;7:21. doi: 10.1186/1472-6807-7-21. BMC Struct Biol. 2007. PMID: 17407565 Free PMC article.

3

Models of beta-amyloid ion channels in the membrane suggest that channel formation in the bilayer is a dynamic process.

Jang H, Zheng J, Nussinov R. Jang H, et al. Among authors: nussinov r. Biophys J. 2007 Sep 15;93(6):1938-49. doi: 10.1529/biophysj.107.110148. Epub 2007 May 25. Biophys J. 2007. PMID: 17526580 Free PMC article.

4

New structures help the modeling of toxic amyloidbeta ion channels.

Jang H, Zheng J, Lal R, Nussinov R. Jang H, et al. Among authors: nussinov r. Trends Biochem Sci. 2008 Feb;33(2):91-100. doi: 10.1016/j.tibs.2007.10.007. Epub 2008 Jan 7. Trends Biochem Sci. 2008. PMID: 18182298 Review.

5

Beta2-microglobulin amyloid fragment organization and morphology and its comparison to Abeta suggests that amyloid aggregation pathways are sequence specific.

Zheng J, Jang H, Nussinov R. Zheng J, et al. Among authors: nussinov r. Biochemistry. 2008 Feb 26;47(8):2497-509. doi: 10.1021/bi7019194. Epub 2008 Jan 24. Biochemistry. 2008. PMID: 18215070

6

Mechanism of membrane permeation induced by synthetic β-hairpin peptides.

Gupta K, Jang H, Harlen K, Puri A, Nussinov R, Schneider JP, Blumenthal R. Gupta K, et al. Among authors: nussinov r. Biophys J. 2013 Nov 5;105(9):2093-103. doi: 10.1016/j.bpj.2013.09.040. Biophys J. 2013. PMID: 24209854 Free PMC article.

7

Oligomerization and nanocluster organization render specificity.

Nussinov R, Jang H, Tsai CJ. Nussinov R, et al. Biol Rev Camb Philos Soc. 2015 May;90(2):587-98. doi: 10.1111/brv.12124. Epub 2014 Jun 11. Biol Rev Camb Philos Soc. 2015. PMID: 24917483 Free PMC article. Review.

8

Dynamic multiprotein assemblies shape the spatial structure of cell signaling.

Nussinov R, Jang H. Nussinov R, et al. Prog Biophys Mol Biol. 2014 Nov-Dec;116(2-3):158-64. doi: 10.1016/j.pbiomolbio.2014.07.002. Epub 2014 Jul 18. Prog Biophys Mol Biol. 2014. PMID: 25046855 Free PMC article. Review.

9

The structural basis for cancer treatment decisions.

Nussinov R, Jang H, Tsai CJ. Nussinov R, et al. Oncotarget. 2014 Sep 15;5(17):7285-302. doi: 10.18632/oncotarget.2439. Oncotarget. 2014. PMID: 25277176 Free PMC article. Review.

10

Mechanisms of membrane binding of small GTPase K-Ras4B farnesylated hypervariable region.

Jang H, Abraham SJ, Chavan TS, Hitchinson B, Khavrutskii L, Tarasova NI, Nussinov R, Gaponenko V. Jang H, et al. Among authors: nussinov r. J Biol Chem. 2015 Apr 10;290(15):9465-77. doi: 10.1074/jbc.M114.620724. Epub 2015 Feb 24. J Biol Chem. 2015. PMID: 25713064 Free PMC article.

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